绝经前后子宫内膜癌生存因素分析

发布时间：2018-01-25 23:55

本文关键词： 绝经前后子宫内膜癌生存因素　出处：《现代肿瘤医学》2016年02期 　论文类型：期刊论文

【摘要】：目的:探讨绝经前后子宫内膜癌的临床资料及预后相关因素。方法:选取2008年1月至2012年3月在唐山市妇幼保健院诊断为子宫内膜腺癌,并接受了手术方法治疗的患者240例。随访共36个月,至2015年3月,分为绝经前和绝经后两组。绝经前115例,绝经后125例,比较两组患者的临床特征、单因素分析两组影响子宫内膜癌患者的预后相关因素及两组间生存率差异。结果:本研究显示绝经前组和绝经后组子宫内膜癌在腺癌类型、深肌层浸润、宫颈受累、淋巴转移、附件受累、病理分级例数、ER、PR阳性例数,比较两者均差异无显著性(P0.05)。两组患者的组织类型、浸润深度、病理分级、附件转移、宫颈受累是影响子宫内膜癌预后的独立因素。绝经前与绝经后患者的3年生存率分别为87%、72%,P0.05,有明显统计学意义。结论:绝经前后子宫内膜癌预后差异显著,绝经是预后的独立因素。
[Abstract]:Objective: to investigate the clinical data and prognostic factors of endometrial carcinoma before and after menopause. Methods: from January 2008 to March 2012, endometrial adenocarcinoma was diagnosed in Tangshan Maternal and Child Health Hospital. 240 patients who received surgical treatment were followed up for 36 months until March 2015. They were divided into premenopausal and postmenopausal groups with 115 cases before menopause and 125 cases after menopause. The clinical characteristics of the two groups were compared. Univariate analysis of the two groups of endometrial cancer patients prognostic factors and survival rate difference between the two groups. Results: this study showed that premenopausal and postmenopausal endometrial carcinoma in the type of adenocarcinoma deep muscle infiltration. Cervical involvement, lymphatic metastasis, adnexal involvement, pathological grade of ERP PR positive cases, there was no significant difference between the two groups, the two groups of tissue types, depth of infiltration. Pathological grade, adnexal metastasis and cervical involvement were independent factors influencing the prognosis of endometrial carcinoma. The 3-year survival rates of premenopausal and postmenopausal patients were 87% and 72% respectively. Conclusion: there is significant difference in prognosis of endometrial carcinoma before and after menopause, and menopause is an independent prognostic factor.
【作者单位】：唐山市妇幼保健院;
【基金】：唐山市科技支撑计划项目(编号:131302117z)
【分类号】：R737.33
【正文快照】： Modern Oncology 2016,24(02):0294-0296者均差异无显著性(P0.05)。两组患者的组织类型、浸润深度、病理分级、附件转移、宫颈受累是影响子宫内膜癌预后的独立因素。绝经前与绝经后患者的3年生存率分别为87%、72%,P0.05,有明显统计学意义。结论:绝经前后子宫内膜癌预后差异

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