活血通管汤联合介入再通术治疗血瘀型输卵管阻塞性不孕的临床观察

发布时间：2018-02-09 04:47

本文关键词： 输卵管阻塞性不孕输卵管介入再通术中医药疗法　出处：《河南中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:本课题通过观察活血通管汤联合介入再通术治疗血瘀型输卵管阻塞性不孕的临床疗效,分析综合治疗后宫内妊娠率、输卵管再通率以及中医症状及体征的改善,探讨其治疗的作用机理,以验证活血通管汤联合介入再通术治疗本病的疗效。希望为输卵管阻塞性不孕患者寻找最佳的治疗方法。方法:本课题选用就诊于河南中医药大学第二附属医院妇产科门诊,符合纳入标准的血瘀型输卵管阻塞性不孕患者60例。采用随机数字表法将研究对象分为治疗组和对照组。两组患者均已行输卵管介入再通术。治疗组于术后第2天开始服用活血通管汤,由河南中医药大学第二附属医院制剂中心统一熬制成200ml袋装,一付药煎成两袋,每日一剂,分早晚温服。对照组于术后第2天开始服用丹桃合剂,早、中、晚于饭后半小时口服,每次20ml。两组患者从次月开始,于月经干净后3天开始服药,连用15天。1个月经周期连续服药15天为1个疗程。次月可以试孕。受孕者停药,未孕者连用6个疗程。结果:治疗组经治疗后宫内妊娠率为56.7%;输卵管通畅的总有效率达到93.3%,痊愈率为80%;盆腔炎相关症状临床痊愈率为53.3%,总有效率为90%。对照组经治疗后宫内妊娠率为23.3%;输卵管通畅的总有效率达到80%,痊愈率为33.3%;盆腔炎相关症状临床痊愈率23.3%,有效率73.3%。比较两组治疗后总有效率及痊愈率,P0.05,有显著性差异,说明治疗组治疗血瘀型输卵管阻塞性不孕比对照组治疗效果好,治愈率高。治疗后治疗组在症状和体征所表现出来的临床症状方面,与对照组相比临床疗效显著,P0.05,具有显著性差异。结论:活血通管汤联合介入再通术治疗血瘀型输卵管阻塞性不孕,具有提高宫内妊娠率,降低输卵管再闭塞率,缓解盆腔炎临床症状,临床疗效显著。充分体现了此综合疗法在治疗近端输卵管阻塞性不孕症方面的优势,具有较高的临床研究价值,值得进一步深入探讨与研究。
[Abstract]:Objective: to observe the clinical effect of Huoxue Tongtuan decoction combined with interventional recanalization in the treatment of obstructive infertility of fallopian tube with blood stasis, and to analyze the improvement of intrauterine pregnancy rate, fallopian tube recanalization rate and the symptoms and signs of traditional Chinese medicine after comprehensive treatment. To explore the mechanism of its treatment, In order to verify the curative effect of Huoxue Tongguan decoction combined with interventional recanalization for the treatment of this disease, we hope to find the best treatment method for the infertile patients with fallopian tube obstruction. Methods: this subject was selected to visit the outpatient department of gynecology and obstetrics of the second affiliated Hospital of Henan University of traditional Chinese Medicine. Sixty cases of oviduct obstructive infertility with blood stasis type were divided into treatment group and control group by random digital table method. The patients in both groups had undergone fallopian tube interventional recanalization. Days began to take Huoxue Tongguo decoction, Prepared by the preparation Center of the second affiliated Hospital of Henan University of traditional Chinese Medicine, 200 ml bags were made, one drug was fried into two bags, one dose was taken in the morning and evening, and the control group began to take Dantao mixture on the second day after operation, morning and middle. Take orally later than half an hour after meal, each time 20ml. Two groups of patients begin from the following month, begin to take medicine 3 days after menstruation clean, use continuously 15 days. 1 menstrual cycle continuously take medicine for 15 days as a course of treatment. The next month can test pregnancy. Results: after treatment, the rate of intrauterine pregnancy was 56.7 in the treatment group; the total effective rate of tubal patency was 93.3and the cure rate was 800.The clinical recovery rate of pelvic inflammation related symptoms was 53.3, and the total effective rate was 900.The control group was treated with treatment. The total effective rate of tubal patency was 80, the cure rate was 33.30.The clinical recovery rate of pelvic inflammation related symptoms was 23.3cm, the effective rate was 73.3%. The total effective rate and cure rate (P0.05) were significantly different between the two groups. The results showed that the treatment group had better therapeutic effect and higher cure rate than the control group in the treatment of oviduct obstructive infertility with blood stasis. The clinical symptoms and signs of the treatment group after treatment were better than those in the control group. Conclusion: Huoxue Tongguan decoction combined with interventional recanalization can improve the rate of intrauterine pregnancy and decrease the rate of reocclusion of fallopian tube. The clinical symptoms of pelvic inflammatory disease are alleviated and the clinical effect is remarkable. It fully reflects the advantages of this comprehensive therapy in the treatment of proximal tubal obstructive infertility. It has a high clinical value and is worthy of further discussion and study.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R711.6

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