腹腔镜及开腹术后联合GnRH-α治疗卵巢内膜样囊肿的疗效比较

发布时间：2018-02-09 11:52

本文关键词： 卵巢内膜样囊肿 Gn RH-α 腹腔镜手术　出处：《临床医药文献电子杂志》2016年49期 　论文类型：期刊论文

【摘要】：目的探讨腹腔镜联合Gn RH-α治疗卵巢内膜样囊肿的安全性及可行性。方法选取2011年1月~2015年1月因卵巢内膜样囊肿在我院行腹腔镜或开腹卵巢囊肿剥除手术术后联合Gn RH-α治疗3~6个周期患者67例的资料。其中腹腔镜下卵巢囊肿剥除36例,开腹卵巢囊肿剥除31例,术后辅以3~6个周期的Gn RH-α治疗,随访至少12个月,比较两组患者术中情况,术后用药后并发症及复发率。结果腹腔镜组全部在腹腔镜下完成,与对照组在年龄,体重指数,囊肿大小和时间上无明显差别;腹腔镜平均手术时间(84.4±31.7)min,短于开腹手术时间(91.3±24.6)min,差异有统计学意义(P0.01);腹腔镜术中平均出血量(65.2±25.1)m L,少于开腹术中平均出血量(106.3±29.2)m L;术后用药并发症:腹腔镜组出现关节酸痛及腰痛等症状21%,与开腹组的23%相比,差异无统计学意义(P0.05),腹腔镜术后出现低雌激素血症14%,较开腹组的16%比较,差异无统计学意义(P0.05),腹腔镜组术后复发率为5.5%,较开腹组的16.1%明显降低。结论腹腔镜术后较开腹术后联合Gn RH-α治疗卵巢内膜样囊肿手术时间短,出血少,复发率低,是治疗卵巢囊肿安全可行的方法。
[Abstract]:Objective to investigate the safety and feasibility of laparoscopy combined with GnRH- 伪 in the treatment of ovarian endometrioid cysts. Methods from January 2011 to January 2015, the patients with ovarian endometrioid cysts underwent laparoscopic or open ovarian cysts excision in our hospital. The data of 67 patients with 3 ~ 6 cycles treated with Gn RH- 伪, including 36 cases of ovarian cyst excision under laparoscope, 31 cases of ovarian cyst excision were treated with 3 ~ 6 cycles of GnRH- 伪. The patients were followed up for at least 12 months to compare the intraoperative condition, postoperative complications and recurrence rate. Results all patients in the laparoscopic group were treated with laparoscopy. There was no significant difference in age, body mass index, cyst size and time between the two groups. The mean operative time of laparoscopy was 84.4 卤31.7 minutes, which was 91.3 卤24.6 minutes shorter than that of open surgery, the difference was statistically significant (P 0.01), the mean blood loss during laparoscopy was 65.2 卤25.1mL, which was less than that during laparotomy (106.3 卤29.2mL). Symptoms such as pain and low back pain, compared with 23% in the open group, There was no significant difference between the two groups (P 0.05). There were 14 cases of hypoestrogenemia after laparoscopy, which was higher than that in the open group (16%%). The recurrence rate of laparoscopy group was 5.5, which was significantly lower than that of open group (16.1%). Conclusion Laparoscopic surgery has shorter operation time, less bleeding and lower recurrence rate than that after laparoscopy combined with GnRH- 伪. It is a safe and feasible method for the treatment of ovarian cyst.
【作者单位】：常州市第二人民医院;
【分类号】：R713.6

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