体外受精-胚胎移植单双胎妊娠相关因素的回顾性分析

发布时间：2018-02-10 14:02

本文关键词： 体外受精胚胎移植单双胎妊娠相关因素　出处：《重庆医学》2017年16期 　论文类型：期刊论文

【摘要】：目的探讨体外受精-胚胎移植影响单双胎妊娠的相关因素及妊娠结局。方法经胚胎移植后,选择女方年龄40岁且35d左右B超检查有孕囊的患者作为研究对象,研究影响单/双胎妊娠相关因素间的关系。结果 (1)Gn用量、Gn天数、用药方案、平均获卵数、平均成熟卵子数、卵子成熟率、正常受精率、可利用胚胎数、移植周期、平均移植胚胎数、完全复苏胚胎数单双胎妊娠组间差异无统计学意义(P0.05);(2)双胎妊娠组的平均复苏胚胎数和平均移植优质胚胎数,显著高于单胎妊娠组(P0.05);(3)双胎妊娠组的优质胚胎数、14d血β-HCG值、早产率和妊娠丢失率极显著高于单胎妊娠组(P0.01);(4)双胎妊娠组的复苏率显著低于单胎妊娠组(P0.05),胚胎停育率极显著低于单胎妊娠组(P0.01);(5)单胎妊娠组的早期妊娠丢失率显著高于双胎妊娠组的(P0.05);(6)异位妊娠率、流产率、活产率、出生体质量和性别比例,单双胎妊娠组间均差异无统计学意义(P0.05)。结论患者优质胚胎数与双胎妊娠密切相关。考虑到优生优育,减少移植优质胚胎能降低多胎妊娠和早产发生率。
[Abstract]:Objective to investigate the related factors and pregnancy outcome of single twin pregnancy affected by in vitro fertilization and embryo transfer. Methods after embryo transfer, women aged 40 years and 35 days old were selected as subjects of study. To study the relationship between the related factors of single / twin pregnancy. Results: the number of days of Gn dosage, the dosage of Gn, the average number of eggs obtained, the average number of mature eggs, the maturation rate of eggs, the normal fertilization rate, the number of available embryos, the transfer period, the average number of eggs matured, the number of embryos available, and the transfer period were studied. There was no significant difference in the average number of embryos transferred and fully resuscitated among the single twin pregnancy group (P 0.05)) the average number of resuscitation embryos and the average number of high quality embryos transferred in the twin pregnancy group. The number of high quality embryos in twin pregnancy group was significantly higher than that in single pregnancy group (P 0.05) and the serum 尾 -HCG value was 14 days after pregnancy. The rate of premature delivery and loss of pregnancy was significantly higher than that of single pregnancy group (P 0.01)) the rate of resuscitation in twin pregnancy group was significantly lower than that in single pregnancy group (P 0.05), and the embryo aborting rate was significantly lower than that in single pregnancy group (P 0.01); the early pregnancy loss rate in single pregnancy group was significantly lower than that in single pregnancy group. The ectopic pregnancy rate was higher in the twin pregnancy group than in the twin pregnancy group. There was no significant difference in abortion rate, live delivery rate, birth weight and sex ratio between single twin pregnancy group and single twin pregnancy group (P 0.05). Conclusion the number of high quality embryos is closely related to twin pregnancy. Reducing the rate of multiple pregnancies and preterm births is associated with a reduction in the transfer of high-quality embryos.
【作者单位】：兰州军区兰州总医院生殖医学中心;
【分类号】：R714.8

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