455例阴道分泌物病原菌检测及药敏情况分析

发布时间：2018-02-14 03:28

本文关键词： 阴道炎白色假丝酵母菌耐药　出处：《重庆医学》2017年21期 　论文类型：期刊论文

【摘要】：目的了解重庆地区妇女阴道病原微生物感染和耐药情况,为及时有效地治疗阴道感染提供理论依据。方法回顾性分析2014年1-12月在该院妇科门诊和住院部就诊的455例疑似有阴道感染者的病原菌培养和药敏结果。结果 455份标本中共培养出病原菌190株,检出率为41.76%,其中革兰阴性菌70株(36.84%),革兰阳性菌36株(29.47%),真菌64株(33.68%),支原体20株(10.53%)。分离的病原菌以白色假丝酵母菌为主(48株,占25.26%),其次为大肠埃希菌(36株,占18.95%)和费氏柠檬酸杆菌(24株,占12.63%);白色假丝酵母菌对氟胞嘧啶全部耐药,部分对伊曲康唑和咪康唑耐药,耐药率分别为2.08%、8.33%;待检菌株均对氟康唑、酮康唑、两性霉素B和制霉菌素敏感;大肠埃希菌和费氏柠檬酸杆菌对亚胺培南和美罗培南均敏感,但对磺胺类、氟喹诺酮类、氨基糖苷类和第3代头孢耐药较明显。结论白色假丝酵母菌、大肠埃希菌和费氏柠檬酸杆菌是重庆地区女性阴道炎的主要病原菌,已有耐药情况发生。
[Abstract]:Objective to investigate the microorganism infection and drug resistance of vaginal pathogens in Chongqing women. Methods in order to provide the theoretical basis for the timely and effective treatment of vaginal infection, a retrospective analysis was made on the pathogen culture and drug sensitivity of 455 suspected vaginal infections in the gynecological outpatient and inpatient department of our hospital from 2014 to December. A total of 190 strains of pathogenic bacteria were cultured. The detectable rate was 41.76, of which 70 were Gram-negative bacteria, 36 were Gram-positive bacteria, 36 were Gram-positive bacteria, 36 were Gram-positive bacteria, 64 were mycoplasma, and 20 were Mycoplasma. The main pathogenic bacteria were Candida albicans (25.26B), followed by Escherichia coli (36 strains). Total resistance of Candida albicans to fluorocytosine, and partial resistance to itraconazole and miconazole were 2.08% and 8.33%, respectively. All strains were resistant to fluconazole and ketoconazole. Amphotericin B and nystatin were sensitive, Escherichia coli and Citrate ferrariae were sensitive to imipenem and meropenem, but they were sensitive to sulfonamides, fluoroquinolones, Conclusion Candida albicans, Escherichia coli and citric acid are the main pathogens of female vaginitis in Chongqing.
【作者单位】：重庆市妇幼保健院妇科病房;重庆市妇幼保健院检验科;
【分类号】：R711.31

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