原因不明月经过少妇女的临床特征和受孕结局

发布时间：2018-02-15 21:19

本文关键词： 月经过少子宫内膜容受性不孕自然流产　出处：《生殖与避孕》2015年10期 　论文类型：期刊论文

【摘要】：目的:寻找原因不明月经过少妇女的实验室和临床特征。方法:110名原因不明月经过少有生育意愿的妇女为研究组及330名月经正常有生育意愿的妇女为对照组,B超观察妇女子宫内膜容受性的临床特征,如内膜厚度、内膜类型、肌层回声、子宫动脉搏动指数以及内膜血流,同时测定黄体中期血雌二醇(E2)、孕酮(P)水平,血凝水平和抗体指标,并对妇女1年内的受孕情况进行随访。结果:研究组妇女的子宫内膜容受性评分低于对照组(9.41±3.02 vs 15.67±2.63,P0.01),黄体中期E2水平较低(172.35±27.54 ng/L vs 220.27±30.28 ng/L,P0.01)。研究组1年内自然受孕率低于对照组(60.0%vs 72.1%,P0.05),孕早期自然流产率(33.3%vs 12.9%,P0.01)较高。结论:原因不明月经过少妇女表现为子宫内膜容受性差,1年内自然受孕率低,建议在孕前给予黄体功能和子宫内膜容受性的检测。
[Abstract]:Objective: to find out the laboratory and clinical characteristics of young women with unexplained menstruation. Methods: 110 women with unexplained menstruation and 330 women with normal menstruation and childbearing intention were studied and compared with those with normal menstruation. To observe the clinical characteristics of endometrial receptivity in women, For example, intimal thickness, endometrial type, myometrium echo, uterine artery pulsatile index and endometrial blood flow, serum estradiol E _ 2, progesterone P) levels, hemagglutination level and antibody index were measured in the middle luteal phase. Results: the endometrial receptivity score of women in the study group was lower than that in the control group (9.41 卤3.02 vs 15.67 卤2.63 P0.01g / L), and E2 level in the middle luteal phase was lower than that in the control group (172.35 卤27.54 ng/L vs 220.27 卤30.28 ng / L P 0.01a). The rate of spontaneous pregnancy in the study group was lower than that in the control group within one year. The rate of spontaneous abortion in the first trimester of pregnancy was 33. 3% vs 12. 9 and P 0. 01). Conclusion: the young women with unknown menstruation showed poor endometrial receptivity and low rate of spontaneous pregnancy within one year. It is recommended that luteal function and endometrial receptivity be measured before pregnancy.
【作者单位】：同济大学附属第一妇婴保健院;
【分类号】：R711.51

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