孕妇人群中无创式血红蛋白检测准确性研究

发布时间：2018-02-23 13:50

  本文关键词： 贫血 血红蛋白 无创检测 孕妇　出处：《中国实用妇科与产科杂志》2015年09期 　论文类型：期刊论文

【摘要】：目的探讨孕妇人群中无创式检测血红蛋白(Hb)结果与静脉血结果的差异和临床意义,为孕妇的贫血筛查提供参考依据。方法采用无创式脉搏血氧血红蛋白仪Or Sense NBM-200检测2014年1月同济大学附属第一妇婴保健院180例孕妇血红蛋白(脉搏血氧血红蛋白,Sp Hb),并同时检测其静脉血红蛋白(venous Hb,v Hb),将结果进行比较,评估其准确性、相关性及一致性。结果在180例孕妇中Sp Hb与v Hb的差异无统计学意义(P=0.463)。Peason相关分析显示,Sp Hb与v Hb相关系数为0.789(P0.001),表明两种方式检测结果有明显相关关系。用Bland-Altman分析Sp Hb与v Hb的差值,结果显示在不贫血孕妇中,平均偏倚为6.6 g/L,95%的一致性界限中的最大差值15.2 g/L为两方式的均值120.0 g/L的12.7%;轻度贫血孕妇中,平均偏倚为7.0 g/L,95%的一致性界限中的最大差值16.6 g/L为两方式的均值108.1 g/L的15.4%;中度贫血孕妇中,平均偏倚为6.2 g/L,95%的一致性界限中的最大差值20.2 g/L为两方式的均值95.6 g/L的21.1%,表明两种检测方法在不同贫血程度的孕妇中均具有良好的一致性,但其准确性随着贫血程度的加重而降低。结论使用NBM-200检测仪得到的Sp Hb与v Hb具有较好的一致性和相关性,虽然准确性有待进一步提升改进,但其具有无创伤和快速的优点,可以更好地为孕妇进行贫血筛查。
[Abstract]:Objective to explore the difference and clinical significance between the results of noninvasive hemoglobin test and venous blood in pregnant women. Methods the non-invasive pulse hemoglobin (or Sense NBM-200) was used to detect the hemoglobin (pulse hemoglobin) of 180 pregnant women in the first maternal and infant health care hospital affiliated to Tongji university in January 2014. The venous hemoglobin was detected at the same time and the results were compared. To assess its accuracy, Results there was no significant difference between SB and vHb in 180 pregnant women. Peason correlation analysis showed that the correlation coefficient between SB and vHb was 0.789 and P0.001, which indicated that there was a significant correlation between the two methods. Bland-Altman analysis showed that there was a significant correlation between the two methods. The difference between SB and v HB, The results showed that the maximum difference of 15.2 g / L was 12.7g / L of 120.0 g / L in non-anemia pregnant women with an average bias of 6.6 g / L 95%. The maximum difference in the consistency limit of an average bias of 7.0 g / L 95% was 16.6 g / L, which was the two-way average of 108.1 g / L 15.4g / L; in moderately anaemic pregnant women, The maximum difference of 20.2 g / L in the consistency limit with an average bias of 6.2 g / L 95% was the average of 95.6 g / L in two ways, indicating that the two methods had good consistency among pregnant women with different levels of anemia. Conclusion the accuracy of SpHb and vHb obtained by using NBM-200 detector has good consistency and correlation. Although the accuracy needs to be further improved, it has the advantages of non-invasive and rapid. Better screening for anaemia in pregnant women.
【作者单位】： 同济大学附属第一妇婴保健院产科;
【分类号】：R714

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