富于细胞性血管纤维瘤3例临床病理分析

发布时间：2018-03-01 14:16

本文关键词： 软组织肿瘤富于细胞性血管纤维瘤病理诊断　出处：《临床与实验病理学杂志》2017年03期 　论文类型：期刊论文

【摘要】：目的探讨富于细胞性血管纤维瘤(cellular angiofibroma,CAF)的临床病理、免疫表型、鉴别诊断及预后。方法对3例CAF行HE和免疫组化Max Vision法染色,分析临床资料并复习相关文献。结果 CAF瘤细胞丰富,呈短梭形,核卵圆形,偶见核分裂象;瘤组织中含大量管壁厚薄不一的血管,部分管壁玻璃样变性,间质可见水肿及黏液样变性。免疫表型:瘤细胞vimentin呈弥漫阳性,CD34、ER、PR呈阳性或部分阳性,SMA、desmin、S-100均呈阴性。结论 CAF是一种少见的间叶性肿瘤,多发于两性生殖区,其镜下以密集的短梭形细胞和丰富血管为特征,治疗以手术切除为主,患者预后良好。
[Abstract]:Objective to investigate the clinicopathology, immunophenotype, differential diagnosis and prognosis of cellular angiofibroma (CAF). Methods three cases of CAF were examined by HE and immunohistochemical Max Vision staining. Results there were plenty of CAF tumor cells with short fusiform shape, oval nucleus and occasional mitosis. There were a large number of vessels with different thickness and thickness in the tumor tissue, some of them were hyaluronic degeneration. Edema and myxoid degeneration were observed in stroma. Immunophenotype: vimentin was diffuse positive and CD34ERP was positive or SMA desminminator S-100 was negative. Conclusion CAF is a rare mesenchymal tumor, which is mainly located in the bilateral reproductive region. It is characterized by dense fusiform cells and abundant blood vessels under microscope. Surgical resection is the main treatment, and the prognosis of the patients is good.
【作者单位】：河南省人民医院病理科;
【分类号】：R737.3

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