不同部位息肉样子宫内膜异位症临床和病理特征11例分析

发布时间：2018-03-04 04:18

本文选题：子宫内膜异位症　切入点：息肉样　出处：《中国实用妇科与产科杂志》2017年11期 　论文类型：期刊论文

【摘要】：目的探讨息肉样子宫内膜异位症(PEM)的临床和病理特征、诊治方法及预后。方法回顾性分析2012年7月至2016年4月于大连医科大学附属大连市妇产医院暨大连市妇幼保健院及大连医科大学附属第一医院收治的11例PEM患者的临床资料,总结其临床和病理特征、诊治方法及预后情况。结果患者发病年龄23~51(41.20±8.97)岁。主要临床表现以病变部位包块、肿瘤引起症状体征及压迫症状体征为主,如盆腔包块、腹股沟区包块、阴道流血、肾积水、腰部疼痛、膀胱占位性病变等,部分临床表现类似恶性肿瘤。大体特征为囊肿内或外生性息肉样肿块;镜下特征具有普通子宫内膜异位症(EM)的病理学特点,病变组织均由子宫内膜样腺体及间质成分构成,但比普通EM更具多样性;免疫组化PEM组织内雌激素受体(ER)、孕激素受体(PR)、CD10、波形蛋白(Vimentin)表达阳性。11例患者均采取手术治疗。10例获得随访,中位随访时间为21个月(9~54个月),1例复发,行二次肿物切除术,10例均存活良好。结论 PEM是EM的一种罕见亚型,临床表现与生长部位相关,呈多样性,诊断主要依靠病理学检查,治疗多以手术为主,预后良好。
[Abstract]:Objective to investigate the clinical and pathological features of polypoid endometriosis (PEM). Methods from July 2012 to April 2016, the clinical data of 11 patients with PEM in Dalian Obstetrics and Gynecology Hospital, Dalian Maternal and Child Health Hospital and the first affiliated Hospital of Dalian Medical University were retrospectively analyzed. The clinical and pathological features, diagnosis and treatment, and prognosis of the patients were summarized. Results the onset age of the patients was 2351or 41.20 卤8.97 years old. The main clinical manifestations were mass of lesion site, symptoms and signs caused by tumor, such as pelvic mass and inguinal mass. Vaginal bleeding, hydronephrosis, lumbar pain, bladder occupying lesions, etc. Some clinical manifestations are similar to malignant tumours. The lesions were composed of endometrioid glands and interstitial components, but they were more diverse than those of normal EM. The expression of estrogen receptor ERA, progesterone receptor (PRP) CD10 and vimentin Vimentin (Vimentin) were detected in PEM tissues by immunohistochemistry. All the 11 cases were followed up by operation. The median follow-up time was 21 months (9 ~ 54 months) and 1 case recurred. Conclusion PEM is a rare subtype of EM, and its clinical manifestation is related to the site of growth and is diverse. The diagnosis depends on pathological examination, and the treatment is mostly surgical, and the prognosis is good. [WT5 "HZ] [WT5" BZ] [WT5 "BZ] [WT5BZ] PEM is a rare subtype of EM.
【作者单位】：大连医科大学附属大连市妇产医院暨大连市妇幼保健院妇科;大连医科大学附属大连市妇产医院暨大连市妇幼保健院病理科;大连医科大学附属第一医院病理科;
【分类号】：R711.71

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