妊娠合并甲状腺功能减退症经激素替代治疗的妊娠结局分析

发布时间：2018-03-04 12:35

本文选题：妊娠　切入点：甲状腺功能减退症　出处：《河北医学》2016年01期 　论文类型：期刊论文

【摘要】：目的:探讨妊娠合并甲状腺功能减退症经过激素替代治疗的妊娠结局。方法:分别选取2010年12月至2014年12月期间41例临床甲状腺功能减退和亚临床甲状腺功能减退孕妇作为研究组(分别记为A组和B组),同期再选取41例甲状腺功能正常孕妇作为对照组(记为C组),给予A、B组激素替代治疗(左旋甲状腺素),而C组不做任何特殊治疗,比较其妊娠结局。结果:A组妊娠期高血压发生率、胎膜早破发生率明显高于C组(4.88%、9.75%),差异比较有统计学意义(P0.05)。其它妊娠并发症发生率方面,三组差异比较无统计学意义(P0.05)。并且,三组新生儿结局比较差异无统计学意义(P0.05)。结论:妊娠合并甲状腺功能减退症经过激素替代治疗后,妊娠期高血压与胎膜早破发生率较高,但其整体妊娠结局与正常孕妇相似。
[Abstract]:Objective: to investigate the outcome of pregnancy with hypothyroidism after hormone replacement therapy. Methods: 41 cases of clinical hypothyroidism and subclinical hypothyroidism were selected from December 2010 to December 2014. During the same period, 41 pregnant women with normal thyroid function were selected as the control group (group C, treated with hormone replacement therapy of group A and B, respectively), while group C, without any special treatment, was given hormone replacement therapy (L-thyroxine). Results the incidence of hypertension complicating pregnancy and premature rupture of membranes in group A was significantly higher than that in group C (4.88 / 9.75), and the difference was statistically significant (P 0.05). There was no significant difference in the incidence of other pregnancy complications among the three groups (P 0.05). Conclusion: after hormone replacement therapy, the incidence of hypertension and premature rupture of membranes in pregnancy with hypothyroidism is higher, but the overall pregnancy outcome is similar to that of normal pregnant women.
【作者单位】：广东省潮州市中心医院妇科/南方医科大学非直属附属医院;
【基金】：广东省科研项目,(编号:科研201204)
【分类号】：R714.256

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