33例非免疫性胎儿水肿临床特点与妊娠结局

发布时间：2018-03-05 23:04

本文选题：胎儿水肿　切入点：产前诊断　出处：《实用妇产科杂志》2015年10期 　论文类型：期刊论文

【摘要】：目的:探讨非免疫性胎儿水肿的病因、超声特点及妊娠结局。方法:对北京大学第三医院产科于2010年1月至2014年6月收治的33例非免疫性胎儿水肿的临床资料进行回顾分析,随访其妊娠结局。结果:33例均经超声诊断,典型胎儿水肿综合征12例,单纯性皮肤水肿17例,单纯性胸腔积液3例,单纯性腹腔积液1例。发病原因中,宫内感染占42.42%(14/33),染色体异常占21.21%(7/33),双胎输血综合征占15.15%(5/33),合并其他系统畸形占12.12%(4/33)。4例胎死宫内,19例选择放弃胎儿引产,10例继续妊娠,严格产前检查至分娩,其中2例新生儿死亡,8例存活。结论:非免疫性胎儿水肿主要表现为单纯性皮肤水肿。宫内感染和染色体异常是导致非免疫性胎儿水肿的主要病因。出现非免疫性胎儿水肿的孕妇,尽早明确病因,对临床早期干预及胎儿预后具有重要意义。
[Abstract]:Objective: to investigate the etiology, ultrasonic characteristics and pregnancy outcome of non-immune fetal edema. Methods: the clinical data of 33 cases of non-immune fetal edema admitted in obstetrics department of Peking University third Hospital from January 2010 to June 2014 were retrospectively analyzed. Results 12 cases of typical fetal edema syndrome, 17 cases of simple skin edema, 3 cases of simple pleural effusion and 1 case of simple celiac effusion were diagnosed by ultrasound. Intrauterine infection accounted for 42.42 / 14 / 33, chromosomal abnormalities 21.21 / 33, twin transfusion syndrome 15.15 / 5 / 33, and other system malformations 12.12 / 4 / 33.4 cases of intrauterine death. 19 cases of intrauterine fetal death chose to give up fetal labor induction in 10 cases to continue pregnancy, and strict antenatal examination was carried out until childbirth. Conclusion: the main manifestation of non-immune fetal edema is simple skin edema. Intrauterine infection and chromosome abnormality are the main causes of non-immune fetal edema. Pregnant women with sexual fetal edema, Early identification of etiology is of great significance for early clinical intervention and fetal prognosis.
【作者单位】：北京大学第三医院;山东省济宁市中区妇幼保健院;
【分类号】：R714.5

【参考文献】