中西医联合治疗多囊卵巢综合征对性激素水平影响分析

发布时间：2018-03-06 18:46

本文选题：多囊卵巢综合征　切入点：调经固冲汤　出处：《辽宁中医杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的:探讨调经固冲汤联合二甲双胍治疗多囊卵巢综合征的临床疗效及对患者新激素水平的影响。方法:选取2015年5月-2016年5月该院收治的多囊卵巢综合征患者198例为研究对象,随机分为观察组与对照组,对照组患者给予二甲双胍治疗,观察组患者给予调经固冲汤联合二甲双胍治疗,治疗结束后对两组患者的临床疗效进行对比分析,同时对治疗前后两组患者性激素水平、子宫内膜厚度、卵巢体积、中医证候评分的变化进行对比。结果:观察组与对照组患者的总有效率分别为92.93%、83.84%,与对照组对比,观察组患者的总有效率明显升高(P0.05);治疗后,观察组与对照组患者的FSH、LH及T水平均较治疗前降低(P0.05),E2水平治疗前后无显著变化(P0.05),且治疗后观察组患者的FSH、LH及T水平明显低于同时期对照组(P0.05);治疗后,观察组与对照组患者的子宫内膜厚度及卵巢体积均较治疗前减少(P0.05),且治疗后观察组患者的子宫内膜厚度及卵巢体积均低于同时期对照组(P0.05);治疗后,观察组与对照组患者的中医证候积分均明显降低(P0.05),且治疗后观察组患者的中医证候积分明显低于同时期对照组(P0.05)。结论:调经固冲汤联合二甲双胍治疗多囊卵巢综合征可有效改善患者性激素水平,疗效显著,值得临床推广应用。
[Abstract]:Objective: to investigate the clinical effect of Tiaojing Guchong decoction combined with metformin in the treatment of polycystic ovary syndrome (PCOS) and its effect on the level of new hormones in patients with PCOS. Methods: from May 2015 to May 2016, the patients with PCOS were selected in our hospital. 198 cases were studied. The patients in the observation group were treated with metformin, and the patients in the observation group were treated with Tiaojingchong decoction combined with metformin. The clinical effects of the two groups were compared and analyzed after the treatment. At the same time, the changes of sex hormone level, endometrial thickness, ovarian volume and TCM syndrome score before and after treatment were compared. Results: the total effective rate of the observation group and the control group was 92.93% and 83.84 respectively, compared with the control group. The total effective rate in the observation group was significantly higher than that in the control group (P 0.05). The levels of FSHLH and T in the observation group and the control group were lower than those in the control group before and after treatment, and the levels of FSHLH and T in the observation group were significantly lower than those in the control group before and after treatment, and after treatment, the levels of FSHLH and T in the observation group were significantly lower than those in the control group before and after treatment. The endometrial thickness and ovarian volume in the observation group and the control group were lower than those in the control group before and after treatment, and the endometrial thickness and ovarian volume in the observation group were lower than those in the control group at the same time. The scores of TCM syndromes in the observation group and the control group were significantly lower than that in the control group after treatment. Conclusion: Tiaojing Guchong decoction combined with metformin is effective in the treatment of polycystic ovary. The combined symptoms can effectively improve the sex hormone level in patients. The curative effect is remarkable, and it is worth popularizing in clinic.
【作者单位】：青海红十字医院妇产科;东莞市人民医院妇科;北京市顺义区医院产科;
【基金】：青海省科技计划项目(2011-Z-726)
【分类号】：R711.75

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