早期子宫内膜癌淋巴结切除术的临床价值分析

发布时间：2018-03-14 16:38

本文选题：早期子宫内膜癌　切入点：腹膜后淋巴结切除　出处：《上海交通大学》2014年硕士论文　论文类型：学位论文

【摘要】：子宫内膜癌是最常见的妇科肿瘤之一，淋巴结转移是其最主要的转移途径。自1988年起，FIGO分期由临床分期转为手术-病理分期。标准的手术分期包括盆腔淋巴结和腹主动脉淋巴结切除，然而对于早期子宫内膜癌患者是否常规行后腹膜淋巴结切除一直存在争议，本综述将对有关子宫内膜癌淋巴结切除的文献进行选择性述评，主要围绕后腹膜淋巴结切除的临床价值、适应症，切除范围、并发症，，如何预测淋巴结转移等方面展开论述。最终得出的结论是：大多数研究证实后腹膜淋巴结切除对淋巴结转移低风险的患者无改善生存率的作用，而对中高风险的子宫内膜癌患者有提高生存率的作用，并对术后辅助治疗起到指导作用。同时关于前哨淋巴结切除的研究还处于初级阶段，尚不能代替系统性淋巴结切除术。
[Abstract]:Endometrial carcinoma is one of the most common gynecological tumors. Since 1988, Figo stage has changed from clinical stage to operation-pathological stage. The standard operative staging includes pelvic lymph node and abdominal aortic lymph node resection. However, there has been controversy about whether early endometrial carcinoma patients should undergo retroperitoneal lymphadenectomy. This review will review the literature on lymph node resection of endometrial carcinoma selectively. The clinical value, indication, resection range, complications of retroperitoneal lymph node resection were mainly discussed. This paper discusses how to predict lymph node metastasis. The final conclusion is that most studies have confirmed that retroperitoneal lymphadenectomy does not improve survival rate in patients with low risk of lymph node metastasis. But it can improve the survival rate of endometrial carcinoma patients with high risk and can guide the postoperative adjuvant therapy. At the same time, the research on sentinel lymph node resection is still in the primary stage, and it is not a substitute for systemic lymphadenectomy.
【学位授予单位】：上海交通大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.33

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