ADC直方图区分宫颈癌常见病理类型的价值

发布时间：2018-03-21 15:54

本文选题：宫颈癌　切入点：弥散加权成像　出处：《中国医学计算机成像杂志》2015年03期 　论文类型：期刊论文

【摘要】：目的:探讨磁共振弥散加权成像(DWI)的表观弥散系数(ADC)直方图对两种常见宫颈癌病理类型的鉴别诊断价值。方法:回顾性分析经病理证实的IB-IIA期宫颈癌37例。在磁共振工作站上绘制整个肿瘤病灶的ADC直方图,记录肿瘤各百分比ADC值及ADCmin、ADCmean、ADCmax;并利用Fire Voxel软件计算出肿瘤ADC直方图曲线的偏度和峰度,分别对鳞癌和腺癌进行统计学比较。结果:鳞癌的ADCmin明显低于腺癌(P=0.042),其余各百分比ADC值、ADCmean、ADCmax在两组间没有统计学差异。鳞癌和腺癌的ADC直方图均为正偏态分布,鳞癌的偏度及峰度均较腺癌高(P=0.027和0.017)。结论:ADC直方图可以客观地提供肿瘤的整体信息,能区别鳞癌和腺癌之间的差异,对宫颈癌的诊断有潜在优势。
[Abstract]:Objective: to investigate the value of apparent diffusion coefficient (IB-IIA) histogram of diffusion-weighted Mr imaging (DWI) in differential diagnosis of two common types of cervical cancer. Methods: 37 cases of pathologically proved cervical carcinoma in IB-IIA were retrospectively analyzed. The ADC histogram of the whole tumor was drawn on the resonance workstation. The percentage of ADC and the mean value of ADCmax were recorded, and the deviation and kurtosis of ADC histogram curve were calculated by Fire Voxel software. Results: the ADCmin of squamous cell carcinoma was significantly lower than that of adenocarcinoma (0.042%). There was no significant difference in the other percentage of ADC between the two groups. The ADC histogram of squamous cell carcinoma and adenocarcinoma were all positive skewed distribution. The skewness and kurtosis of squamous cell carcinoma are higher than that of adenocarcinoma. Conclusion the ratio ADC histogram can objectively provide the overall information of the tumor, and can distinguish the difference between squamous cell carcinoma and adenocarcinoma, and has potential advantages in the diagnosis of cervical cancer.
【作者单位】：同济大学附属第一妇婴保健院放射科;
【分类号】：R445.2;R737.33

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