子宫颈癌筛查方法的比较研究

发布时间：2018-03-24 23:27

本文选题：子宫颈癌　切入点：巴氏细胞学　出处：《中国当代医药》2016年30期

【摘要】：目的探讨传统巴氏细胞学筛查、液基细胞学筛查以及人乳头瘤病毒(HPV)DNA检测在子宫颈癌患者筛查中的应用效果。方法选取2013年1月~2016年2月在我院接受子宫颈癌筛查患者800例作为研究对象,患者均给予传统巴氏细胞学筛查、液基细胞学筛查、HPV DNA筛查以及阴道镜检查,以患者病理组织学筛查结果作为最终标准,对比不同检查方法的检查结果。结果 800例患者经巴氏涂片法筛查结果显示阳性者102例(12.8%)、液基细胞学筛查结果显示阳性者112例(14.0%)、HPV DNA筛查方法显示阳性患者205例(25.6%)、病理学筛查结果显示为103例(12.9%),且液基细胞学筛查结果与病理学筛查结果一致性最高,与其他两种筛查方法比较,差异有统计学意义(P0.05)。结论液基细胞学可以作为子宫颈癌以及癌前病变的首选筛查方法,其与患者病理学检查结果一致性最高,值得临床推广。
[Abstract]:Objective to explore the traditional Pap cytologic screening, Liquid based cytological screening and human papillomavirus HPV DNA detection were used in cervical cancer screening. Methods 800 cervical cancer screening patients were selected from January 2013 to February 2016. All patients were given traditional pasteurized cytology screening, liquid based cytological screening and colposcopy, and the final criteria were histopathological screening results. Results the screening results of 800 patients with pasteurized smears showed that 102 cases were positive, and 112 cases showed positive by liquid-based cytology. 205 cases with positive DNA were found to be positive by the method of Pap smear, the results of liquid based cytology showed that there were 205 cases with positive HPV-HPV-HPV-HPV-HPV-HPV-HPV-HPV-HPV-HPV-HPV-HPV-DNA. The results of pathological screening showed that 103 cases had the highest consistency with the results of pathological screening, and the results of liquid-based cytology showed the highest consistency with the results of pathological screening. Compared with the other two screening methods, the difference was statistically significant (P 0.05). Conclusion liquid based cytology can be used as the preferred screening method for cervical cancer and precancerous lesions.
【作者单位】：江西省乐平市人民医院;
【基金】：江西省景德镇市医疗卫生指导性科技计划项目(cf200607)
【分类号】：R737.33

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