处理前精液参数与宫腔内人工授精妊娠率的相关性研究

发布时间：2018-03-25 15:42

本文选题：处理前精液参数　切入点：宫腔内人工授精　出处：《实用医学杂志》2015年12期

【摘要】：目的:研究处理前精液参数与宫腔内人工授精(IUI)妊娠率的关系。方法:回顾性分析我院生殖科284个IUI周期,参考WHO第5版精液参数下限,将处理前丈夫精液如下分组:禁欲时间(3 d、3~5d、5 d)、黏稠度(正常黏稠、高度黏稠)、p H值(7.2、7.2~7.4、7.5~7.8)、浓度(20×106/m L、20~40×106/m L、40×106/m L)、前向运动精子百分比(40%、40%~50%、50%)、前向运动精子总数[20×106、(20~50)×106、(50~100)×106、100×106],分别比较各组间的周期妊娠率。结果 :共完成284个IUI周期,临床妊娠47周期,总临床妊娠率16.5%;处理前精液黏稠度、p H值、浓度、前向运动精子百分比、前向运动精子总数各组妊娠率虽未见统计学差异(P0.05),但高度黏稠、p H值7.2、前向运动精子总数20×1063组与对应组别比较,妊娠率均降低;禁欲时间3 d组妊娠率较其他组显著降低(P0.05)。结论 :处理前精液浓度、p H值、前向运动精子百分率与IUI临床妊娠率应无明显相关性,而禁欲时间、黏稠度、前向运动精子总数与IUI临床妊娠率是否存在相关性,还需统计更多的周期数。
[Abstract]:Objective: to study the relationship between semen parameters before treatment and pregnancy rate of intrauterine insemination. Methods: 284 cycles of IUI were analyzed retrospectively and the lower limit of semen parameters of WHO version 5 was consulted. The former husband's semen was divided into the following groups: abstinence time was 3 days, 3 days, 5 days, 5 days, consistency (normal viscosity, The H value of highly viscous sperm was 7.27.47.47.57.8U, the concentration was 20 脳 106mL / L, the concentration was 20 脳 106mL / L, 40 脳 106mL / mL, the percentage of forward motility spermatozoa was 404040ml / mL, and the total number of motility sperm was 20 脳 10650mg / kg 脳 106100 脳 106.Results: a total of 284cycles of IUI were completed, 47 cycles of clinical pregnancy were completed, and the total number of motility spermatozoa was 106100 脳 106.Results: a total of 284cycles were completed, 47 cycles of clinical pregnancy were completed, and the total number of motility spermatozoa was 106100 脳 106.Results: a total of 284cycles were completed, 47 cycles of clinical pregnancy were completed. The total clinical pregnancy rate was 16.5.The semen viscosity, concentration, percentage of motility sperm before treatment, Although there was no statistical difference in the pregnancy rate among the groups with the total number of forward motile sperm, the pregnancy rate was decreased in the group of 20 脳 1063 of the total number of forward motile sperm compared with the corresponding group, but the value of H was 7.2 in the group of highly viscous motile spermatozoa. The pregnancy rate of the abstinence time 3 days group was significantly lower than that of the other groups. Conclusion: there is no significant correlation between the sperm concentration, the percentage of forward motility sperm and the clinical pregnancy rate of IUI before treatment, but the abstinence time and the consistency of abstinence. Whether there is a correlation between the total number of forward motile sperm and the clinical pregnancy rate of IUI needs to count more cycles.
【作者单位】：广东省中医院生殖医学科;
【分类号】：R714.8

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