怀孕早期负面情绪对异常妊娠结局的影响研究

发布时间：2018-03-26 07:33

  本文选题：负面情绪　切入点：精神挫折　出处：《卫生研究》2015年01期

【摘要】：目的探讨负面情绪与异常妊娠结局之间的关系。方法通过调查在北京协和医院就诊的200名异常妊娠孕妇及200名与其年龄相匹配(±2岁)的、分娩正常新生儿的产妇进行病例-对照研究,应用多因素条件Logistic逐步回归进行分析。结果病例组孕妇在怀孕早期经受较大精神挫折以及经常情绪紧张、感到有压力或焦虑的比例显著高于对照组(P0.05),将负面情绪进行分级(0=无负面情绪,1=经常情绪紧张,感到有压力或焦虑,2=经受较大精神挫折,同时有/无经常情绪紧张,感到有压力或焦虑),以无负面情绪为参照,发现随着负面情绪程度的加重,孕妇发生异常妊娠的相对危险度有增加趋势(趋势性χ2=43.08,P0.01),其OR值分别为3.67和14.14。在通过多因素分析调整了其他危险因素的作用之后,怀孕早期的负面情绪仍显著增加孕妇发生异常妊娠的相对危险度(OR=4.04,95%CI=2.01~8.09)。结论怀孕早期的负面情绪可能是孕妇发生异常妊娠的危险因素。
[Abstract]:Objective to explore the relationship between negative emotions and abnormal pregnancy outcomes. Methods through investigation in Peking Union Medical College Hospital from 200 abnormal pregnant women and 200 healthy age-matched (+ 2 years), normal newborn delivery women were case-control study, using multivariate Logistic regression analysis. Results the cases in pregnant women in early pregnancy, often undergo large spiritual frustration and emotional tension, feel pressure or anxiety was significantly higher than the control group (P0.05), the negative emotions were graded (0= no 1= negative emotions, often emotional tension, stress or anxiety, 2= undergo large mental frustration, and often with / without emotional tension, feel there is stress or anxiety), with no negative emotions as a reference, with the increasing degree of negative emotions, pregnant women abnormal pregnancy relative risk increased trend (x 2=4 3.08, P0.01), after which the OR values were 3.67 and 14.14. in multivariate analysis adjusting for other risk factors, early pregnancy, negative emotions of pregnant women still significantly increased relative risk of abnormal pregnancy (OR=4.04,95%CI=2.01~8.09). Conclusion in early pregnancy, negative emotions may be a risk factor for abnormal pregnancy in pregnant women.

【作者单位】： 中国疾病预防控制中心环境与健康相关产品安全所;北京协和医院产科;
【基金】：中国疾病预防控制中心环境与健康相关产品安全所中青年科学基金
【分类号】：R715.3
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本文编号：1666975