术中自体血回收用于产科手术的可行性研究

发布时间：2018-03-28 01:34

本文选题：术中自体血回收　切入点：组织因子　出处：《中国输血杂志》2016年07期

【摘要】：目的通过定量分析血液中的甲胎蛋白及组织因子来判断产科术中回收血液的质量。方法 2014年10月-2015年4月本院妇产科收治的前置胎盘、胎盘早剥及胎盘植入拟行剖宫产患者10例,分别于右颈内静脉穿刺置管即刻(T1)、切皮(T2)、胎盘剥离即刻(T3)、胎盘剥离5 min(T4)及30 min(T5)后各个时间点抽取中心静脉血液,并留取经自体血回收机洗涤后的血液(T6)及白细胞过滤器过滤后血液(T7)。随后对收集的标本用ELISA法对血清甲胎蛋白及血浆组织因子进行定量分析。结果血液中的甲胎蛋白经血液回收机洗涤后显著降低,T1、T2、T3、T4、T5各时刻的血清甲胎蛋白比较差异不具统计学意义(P0.05),分别与T6、T7时刻的甲胎蛋白比较,差异具统计学意义(P0.01),T6与T7时刻的甲胎蛋白比较,差异不具统计学意义(P0.05)。各时刻的血浆组织因子比较差异不具统计学意义(P0.05)。结论产科术中经自体血回收机回收洗涤的血液,联合使用白细胞过滤器回输体内理论上可行。
[Abstract]:Objective to determine the quality of recovered blood by quantitative analysis of alpha-fetoprotein and tissue factors in blood. Methods placenta previa was admitted to our hospital from October 2014 to April 2015. Ten patients with placental abruption and placenta accreta were treated by caesarean section. Central venous blood was extracted at each time point after right internal jugular vein puncture and catheterization. The blood samples were collected after washing by autologous blood recovery machine (T6) and leucocyte filter filtration. The serum AFP and plasma tissue factors were analyzed quantitatively by ELISA method. There was no significant difference in serum alpha-fetoprotein between T1T1T2T2T3T4T4T5 and T6 T7 after washing with a blood recovery machine, and there was no significant difference in serum Alpha-fetoprotein (AFP) between T6 and T7, and there was no significant difference in serum Alpha-fetoprotein (AFP) between T6 and T7. The difference was statistically significant (P 0.01) between T6 and T7, the difference was not statistically significant (P 0.05). There was no significant difference in plasma tissue factor (P 0.05). Conclusion during obstetrical operation, the washed blood was recovered by autologous blood recovery machine. The combined use of white blood cell filter is theoretically feasible.
【作者单位】：民航总医院麻醉科;民航总医院妇产科;
【分类号】：R457.1;R719

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