中晚期宫颈癌外照射阶段三维适形放疗和共面等分设野调强放疗计划探讨

发布时间：2018-03-28 02:11

本文选题：宫颈癌　切入点：三维适形　出处：《河北医学》2016年11期

【摘要】：目的:探讨三维适形放射治疗(3D-CRT)和共面等分设野调强放射治疗(IMRT)对宫颈癌患者外照射阶段计划靶区以及周围危及器官受照剂量的差异。方法:选取2014至2015年在我院放化疗中心住院的21例宫颈癌患者,行CT扫描,设靶区,勾画周围危及器官,剂量50Gy。分别行3DCRT和共面等分设野IMRT计划,计算靶区剂量均匀度指数(HI)、适形度指数(CI)、照射最大剂量、照射最小剂量、照射平均剂量及周围器官的照射体积,计算结果并对比分析。结果:5F-IMRT、7F-IMRT、9F-IMRT的靶区适形度优于3D-CRT;在受累的周围器官保护方面,IMRT计划均优于3D-CRT,差异具有统计学意义(P0.05)。结论:中晚期宫颈癌患者外照射阶段IMRT计划在靶区适形度及对周围组织器官的保护方面要好于3D-CRT,同时也表明5野与7野、9野比较,在治疗的经济效益方面有优势。
[Abstract]:Objective: to investigate the difference of radiation doses in the planned target area and surrounding organs of patients with cervical cancer during the external irradiation stage by using 3D conformal radiotherapy (3D-CRT) and coplanar intensity modulated radiation therapy (IMRT). Methods: from 2014 to 2015, the dose of radiation was selected in our hospital. 21 patients with cervical cancer in the center of radiotherapy and chemotherapy, Ct scanning was performed, target area was set up, peri-organ was delineated, dose was 50 Gy.The 3DCRT and coplanar field IMRT plan were used to calculate the dose evenness index of target area, conformability index, maximum dose and minimum dose, respectively. The average dose of exposure and the volume of exposure to the surrounding organ, Results the conformal degree of target area of 7F-IMRTT 9F-IMRT was better than that of 3D-CRT, and the plan of IMRT was better than 3D-CRT in the protection of affected peripheral organs, the difference was statistically significant (P0.055.Conclusion: IMRT plan in external irradiation stage of patients with advanced cervical cancer is better than 3D-CRT. The conformal degree of target area and the protection of surrounding tissues and organs were better than that of 3D-CRT. There are advantages in the economic benefits of treatment.
【作者单位】：河北省承德市中心医院放化疗中心;
【基金】：河北省承德市科学技术局项目,(编号:20151016)
【分类号】：R737.33

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