妊娠期高血压疾病母体心脏形态功能与新生儿预后的关系

发布时间：2018-03-29 10:31

本文选题：妊娠　切入点：高血压　出处：《广东医学》2017年21期

【摘要】：目的分析妊娠期高血压疾病患者母体心脏形态功能的改变与新生儿预后指标的相关性。方法选择妊娠期患者157例进行超声心动图检查,根据纳入及排除标准分为高血压组与血压正常组。跟踪随访患者终止妊娠方式及分娩孕周、新生儿预后评估指标。比较两组间母体心脏形态功能及新生儿预后指标,并进一步分析新生儿预后指标与母体心脏形态功能的相关性。结果两组间比较显示,母体心脏形态功能方面,左房内径(LA)、室间隔厚度(IVS)、左室后壁(LVPW)、左室质量(LVM)、左室质量指数(LVMI-BSA、LVMI-heigh2.7)及心包积液(PE)、主动脉瓣反流(AR)、二尖瓣反流(MR)、左室舒张功能异常的比例,高血压组均高于血压正常组,差异有统计学意义(P0.05);新生儿预后指标方面,新生儿Apgar-0评分、体重、身长及头围,高血压组均低于血压正常组,差异有统计学意义(P0.01)。相关性分析显示,LA与Apgar-0呈负相关(r=-1.91),IVS与新生儿体重呈负相关(r=-0.19);PE与Apgar-0、新生儿体重、身长及头围均呈负相关(r=-0.34、-0.25、-0.21);上述相关性均有统计学意义(P0.05)。结论妊娠期高血压疾病母体心脏具有LA增大、左室舒张功能异常、AR、MR及心包积液等超声表现,妊娠期高血压对母胎的影响具有一致性,LA、IVS、PE能一定程度反映母胎的损伤程度,为临床治疗和终止妊娠提供依据。
[Abstract]:Objective to analyze the relationship between maternal heart function and neonatal prognosis in hypertensive disorder complicating pregnancy. According to the criteria of inclusion and exclusion, the patients were divided into hypertension group and normal blood pressure group. The termination of pregnancy, gestational weeks of delivery and neonatal prognosis were followed up. The maternal heart function and neonatal prognosis were compared between the two groups. The relationship between maternal heart morphology and maternal heart function was further analyzed. Results the comparison between the two groups showed that the maternal heart morphology and function, Left atrial diameter (LAA), interventricular septal thickness (IVS), left ventricular posterior wall (LVPWN), left ventricular mass (LVMN), left ventricular mass index (LVMI-BSAL LVMI-heigh2.7), pericardial effusion (PEV), aortic regurgitation (ARN), mitral regurgitation (MRR), left ventricular diastolic dysfunction (LVVD) in hypertension group were higher than those in normal blood pressure group (P < 0.05). The difference was statistically significant (P 0.05), the neonatal prognostic indexes, neonatal Apgar-0 score, body weight, body length, head circumference, hypertension group were lower than those of normal blood pressure group. The correlation analysis showed that there was a negative correlation between LA and Apgar-0. There was a negative correlation between Apgar-0 and neonatal weight. There was a negative correlation between head circumference and body length. Conclusion the maternal heart of hypertensive disorder complicating pregnancy is characterized by LA enlargement, left ventricular diastolic dysfunction and pericardial effusion. The effect of gestational hypertension on maternal and fetal development is consistent. Lafan IVSPE can reflect the degree of maternal fetal injury to a certain extent and provide evidence for clinical treatment and termination of pregnancy.
【作者单位】：广州医科大学附属第三医院超声医学科;
【分类号】：R714.246

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