胎膜早破对孕母感染及早产儿结局的影响

发布时间：2018-03-31 18:52

  本文选题：胎膜早破　切入点：潜伏期　出处：《中国当代儿科杂志》2017年08期

【摘要】：目的探讨胎膜早破(PROM)对孕母感染及早产儿结局的影响。方法以441例早产儿及其母亲(387例)为研究对象,根据孕母是否胎膜早破分为对照组(无PROM,104例),PROM时间72 h组(90例)及≥72 h组(193例)。比较各组母、婴的临床特点及并发症差异。结果破膜时间≥72 h组孕母的年龄、脐血管炎发生率以及抗生素应用高于对照组和破膜时间72 h组(P0.05);中-重度绒毛膜羊膜炎的发生率高于对照组(P0.05),但与72 h组的差异无统计学意义(P0.05)。破膜时间≥72 h组早产儿肺炎、颅内出血的发生率高于对照组和破膜时间72 h组(P0.01);先天性感染的发生率、住院天数高于对照组(P0.05),但与72 h组的差异无统计学意义(P0.05)。多因素回归分析显示,破膜时间≥72 h是早产儿发生肺炎(P0.05)及颅内出血(P0.05)的独立危险因素。结论破膜时间≥72 h使孕母胎盘炎症发生风险增加,而且与早产儿肺炎、颅内出血发生相关。
[Abstract]:Objective to investigate the effect of premature rupture of membranes (PROM) on maternal infection and outcome of premature infants. Methods 441 premature infants and 387 mothers were studied. According to whether the pregnant mother had premature rupture of membranes, they were divided into two groups: the control group (90 cases without promazine for 72 h) and the group of 193 cases with 鈮，

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