子宫内膜异位症腹腔镜治疗后行体外受精-胚胎移植的妊娠时机

发布时间：2018-04-02 00:12

本文选题：子宫内膜异位症　切入点：不育　出处：《广东医学》2015年10期

【摘要】：目的分析探讨子宫内膜异位症(EMT)腹腔镜治疗后行体外受精-胚胎移植(IVF-ET)的妊娠时机和影响因素。方法选取诊断为EMT经腹腔镜治疗后需行IVF-ET治疗的120例不育症患者为研究对象,按照患者术后妊娠时间1年(A组)、2年(B组)及3年(C组)进行分组,观察3组患者术后妊娠情况。分析行IVF-ET治疗的不育症患者的妊娠率与术后时间的关系。选用年龄、是否使用促性腺激素释放激素激动剂(GnRH-a)及EMT分期进行多因素logistic回归,分析其妊娠相关的影响因素。结果随访患者术后第1、2、3年(行IVF-ET治疗)妊娠率分别为55.00%、32.50%、25.00%;术后第1年与术后第2年及第3年妊娠率比较,差异均有统计学意义(P0.05);单因素分析结果发现,患者的年龄、术后是否使用避孕措施、术后GnRH-a使用情况和EMT分期与术后1年内患者妊娠情况有明显相关性(P0.05);多因素条件logistic回归分析显示,高龄育龄期女性、术后是否使用避孕措施、术后使用GnRH-a和EMT分期与术后1年内妊娠情况有关(P0.05)。结论 EMT腹腔镜治疗后行IVF-ET的妊娠时机与多种因素有关,以第1年内妊娠率最高,且高龄育龄期女性、术后使用GnRH-a和EMT分期与术后1年内辅助妊娠情况有明显相关性。
[Abstract]:Objective to analyze the pregnancy timing and influencing factors of IVF-ETT after laparoscopic treatment of endometriosis. Methods 120 infertile patients who were diagnosed as EMT who needed IVF-ET treatment after laparoscopic treatment were selected as the study objects. According to the time of pregnancy 1 year after operation, group B (2 years) and group C (3 years), the pregnancy status of the three groups was observed, and the relationship between pregnancy rate and postoperative time of infertility treated with IVF-ET was analyzed. Whether gonadotropin releasing hormone agonist (GnRH-a) and EMT staging were used for multivariate logistic regression, Results the pregnancy rates in the first and third year (IVF-ET treatment) were 55.00 and 32.50 and 25.00, respectively, and the pregnancy rates in the first year and the second and the third year after operation were compared. The difference was statistically significant (P 0.05). Univariate analysis showed that the age of the patients and whether or not to use contraception after operation, There was a significant correlation between postoperative GnRH-a use and EMT stage and pregnancy status within 1 year after operation (P 0.05). Multivariate conditional logistic regression analysis showed that the elderly women of childbearing age were using contraception after operation. GnRH-a and EMT stages were associated with pregnancy within 1 year after operation (P 0.05). Conclusion the pregnancy timing of IVF-ET after EMT laparoscopic therapy is related to many factors, and the pregnancy rate is the highest in the first year, and the elderly women of childbearing age have the highest pregnancy rate. The use of GnRH-a and EMT stages was significantly correlated with the degree of assisted pregnancy within 1 year after operation.
【作者单位】：海南省农垦总医院生殖科;
【分类号】：R714.8

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