加味苍附导痰汤辅助治疗多囊卵巢综合征效果观察

发布时间：2018-04-10 17:24

本文选题：多囊卵巢综合征 + 加味苍附导痰汤　；参考：《人民军医》2016年12期

【摘要】：目的:观察加味苍附导痰汤联合炔雌醇环丙孕酮片治疗多囊卵巢综合征(PCOS)的临床疗效。方法:选择我院门诊就诊的PCOS 100例,随机分为观察组与对照组各50例。对照组于月经周期内或黄体酮撤退性出血第5天口服炔雌醇环丙孕酮片;观察组在口服炔雌醇环丙孕酮片的基础上,加用加味苍附导痰汤治疗。两组均21天为1个疗程,连续3个疗程。比较两组临床疗效,分别于治疗前、疗程结束时及1个月后随访时测定黄体生成激素(LH)、尿促卵泡素(FSH)、雌二醇(E2)、催乳素(PRL)及睾酮(T)水平;采用Ferriman-Gallwey评分标准评估多毛体征,痤疮评分系统记录痤疮严重程度,中医症候评分表评估月经不调发生情况以及卵巢体积变化情况。结果:观察组总有效率88.0%,显著高于对照组的60.0%(P0.05)。两组疗程结束后及1个月随访时血清LH、FSH、E2、PRL、T水平均较治疗前显著降低,卵巢体积较治疗前显著缩小,毛发评分、痤疮评分、月经不调评分均较治疗前显著降低(P0.05)。疗程结束时,观察组上述血清指标及卵巢体积均显著低于对照组(P0.05);1个月后随访时,观察组血清LH、E2、PRL、T水平及毛发评分显著低于对照组(P0.05)。结论:加味苍附导痰汤联合炔雌醇环丙孕酮片治疗PCOS疗效优于单用炔雌醇环丙孕酮片。
[Abstract]:Objective: to observe the clinical effect of Cangfu Doutan decoction combined with ethylestradiol Cyproprogesterone tablet in the treatment of polycystic ovary syndrome (PCOS).Methods: 100 cases of PCOS were randomly divided into two groups: observation group (n = 50) and control group (n = 50).The control group received oral ethylestradiol cycloprogestrel tablets during menstrual cycle or the 5th day of withdrawal hemorrhage of progesterone, and the observation group was treated with Cangfu Doutan decoction on the basis of oral oral ethylestradiol cycloproprogesterone tablets.Two groups were 21 days as a course of treatment, 3 consecutive courses.Acne scoring system recorded the severity of acne, TCM symptom score table to assess the occurrence of menstrual irregularities and ovarian volume changes.Results: the total effective rate of the observation group was 88.0, which was significantly higher than that of the control group.At the end of the course of treatment and 1 month follow-up, the serum levels of serum LHFSHSHE2PRLT were significantly lower than those before treatment, ovarian volume was significantly reduced, hair score, acne score and menstrual disorder score were all significantly lower than that before treatment (P 0.05).At the end of the course of treatment, the serum parameters and ovarian volume in the observation group were significantly lower than those in the control group (P 0.05), and at the follow-up of one month, the levels of serum LHN E2P PRLT and the hair score in the observation group were significantly lower than those in the control group (P 0.05).Conclusion: the curative effect of modified Cangfu Doutan decoction combined with ethylestradiol cycloproprogesterone tablet in the treatment of PCOS is better than that of single use of ethylestradiol cycloproprogesterone tablet.
【作者单位】：陆军总医院263临床部中医科;
【分类号】：R711.75

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