血清TNF-α与Npt和G-CSF对胎膜早破合并羊膜腔感染的诊断分析
发布时间：2018-04-12 10:16
本文选题：TNF-α + Npt ； 参考：《中华医院感染学杂志》2017年19期
【摘要】：目的探讨血清肿瘤坏死因子-α(TNF-α)、新喋呤(Npt)、粒细胞集落刺激因子(G-CSF)用于胎膜早破合并羊膜腔感染诊断的临床价值。方法 2013年6月-2016年5月期间的68例胎膜早破患者作为观察组,同期70例正常孕妇作为对照组,对比两组血清TNF-α、Npt、G-CSF水平;根据是否合并羊膜腔感染将68例胎膜早破患者分为羊膜腔感染组36例与非羊膜腔感染组32例,对比两组患者血清TNF-α、Npt、G-CSF水平;对比羊膜腔感染患者不同严重程度患者的血清TNF-α、Npt、G-CSF水平。结果观察组血清TNF-α、Npt、G-CSF水平分别为(776.82±89.61)ng/L、(16.91±4.11)mmol/L、(109.33±21.71),均显著高于对照组的(478.53±90.10)ng/L、(7.24±4.02)mmol/L、(82.32±21.67)(P0.01);合并羊膜腔感染组血清TNF-α、Npt、G-CSF水平分别为(784.82±85.10)ng/L、(18.74±1.51)mmol/L、(115.36±22.01)显著高于无羊膜腔感染组(492.61±84.98)ng/L、(9.82±1.48)mmol/L、(93.22±21.89)(P0.01);胎膜早破合并羊膜腔感染患者中,血清TNF-α、Npt、GCSF水平随羊膜腔感染程度的加重表现出显著增高趋势(P0.01)。结论胎膜早破合并羊膜腔感染患者血清TNF-α、Npt、G-CSF水平明显增高,且随羊膜腔感染严重程度的加重而显著上升,可在一定程度上对胎膜早破合并羊膜腔感染起到有效的预测和早期诊断作用。
[Abstract]:Objective to investigate the clinical value of serum tumor necrosis factor- 伪 (TNF- 伪), neopterin, neopterin and granulocyte colony stimulating factor (G-CSF) in the diagnosis of premature rupture of membranes with amniotic infection.Methods from June 2013 to May 2016, 68 patients with premature rupture of membranes were treated as observation group and 70 normal pregnant women as control group.68 patients with premature rupture of amniotic membrane were divided into amniotic infection group (n = 36) and non-amniotic infection group (n = 32) according to whether they were complicated with amniotic cavity infection.缁撴灉瑙傚療缁勮娓匱NF-伪,Npt,G-CSF姘村钩鍒嗗埆涓，
本文编号：1739313
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