桂枝茯苓胶囊辅助治疗输卵管阻塞性不孕的临床疗效及对TNF-α的影响

发布时间：2018-04-15 18:18

本文选题：输卵管阻塞性不孕 + 桂枝茯苓胶囊　；参考：《辽宁中医杂志》2017年08期

【摘要】：目的:探讨桂枝茯苓胶囊辅助治疗输卵管阻塞性不孕的临床疗效及对肿瘤坏死因子-α(TNF-α)的影响。方法:选取2015年6月—2016年12月本院收治的输卵管阻塞性不孕患者82例为研究对象,随机分为治疗组与对照组,对照组患者给予输卵管通液术治疗,治疗组患者在输卵管通液术的基础上给予桂枝茯苓胶囊辅助治疗,在治疗结束后对两组的临床疗效进行评价,对比治疗前后两组患者中医证候积分、治疗后输卵管通畅情况及血清TNF-α水平。结果:治疗组与对照组患者的总有效率分别为92.68%、78.05%,治疗组患者的总有效率显著高于对照组(P0.05);两组血清TNF-α水平在治疗前对比无显著差异(P0.05),治疗后两组患者血清TNF-α水平均较治疗前显著降低(P0.05),且治疗组患者血清TNF-α水平低于对照组(P0.05);两组患者治疗前中医证候积分对比无显著差异(P0.05),治疗后两组中医证候积分均显著降低,且治疗组患者低于对照组(P0.05);治疗组患者输卵管通畅率显著高于对照组,输卵管通而不畅、积水及堵塞率显著低于对照组(P0.05)。结论:桂枝茯苓胶囊辅助宫腔镜输卵管通液术治疗输卵管阻塞性不孕的可显著提高临床疗效,并改善输卵管通畅程度及血清TNF-α水平,值得临床推广。
[Abstract]:Objective: to investigate the clinical effect of Guizhi Fuling capsule on tubal obstructive infertility and its effect on tumor necrosis factor- 伪 (TNF- 伪).Methods: 82 patients with tubal obstructive infertility from June 2015 to December 2016 were randomly divided into two groups: the treatment group and the control group. The patients in the control group were treated with salpingostomy.The patients in the treatment group were treated with Guizhi Fuling capsule on the basis of tubal fluid therapy. After the treatment, the clinical effects of the two groups were evaluated, and the TCM syndromes scores of the two groups were compared before and after the treatment.After treatment, tubal patency and serum TNF- 伪 level were observed.Results: the total effective rate of the treatment group and the control group were 92.68 and 78.05, respectively. The total effective rate of the treatment group was significantly higher than that of the control group (P 0.05), the serum TNF- 伪 level of the two groups had no significant difference before and after treatment, and the serum TNF- 伪 level of the two groups after treatment was higher than that of the control group (P < 0.05).The serum TNF- 伪 level of the patients in the treatment group was lower than that in the control group, and there was no significant difference in the scores of TCM syndromes between the two groups before treatment.The rate of tubal patency in the treatment group was significantly higher than that in the control group, and the rates of hydrops and blockage were significantly lower in the treatment group than in the control group.Conclusion: Guizhi Fuling capsule assisted hysteroscopic tubal tubal operation can significantly improve the clinical efficacy, improve the degree of tubal patency and the level of serum TNF- 伪, and is worthy of clinical promotion.
【作者单位】：广州中医药大学;哈尔滨医科大学第二临床医学院;广东省中医院妇科;
【基金】：广东省科技计划项目(2013B032500013)
【分类号】：R711.6

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