妊娠中期OGTT正常的孕妇妊娠晚期体质量增长过快对妊娠期并发症及围生期结局的影响

发布时间：2018-04-19 00:33

本文选题：妊娠晚期 + 体质量增长　；参考：《实用妇产科杂志》2017年11期

【摘要】：目的:探讨妊娠中期口服75 g葡萄糖耐量(OGTT)正常的孕妇妊娠晚期体质量增长过快对妊娠期并发症及围生期结局的影响。方法:随机选择2015年10月至2016年9月在天津医科大学第二医院产科产检并分娩,妊娠前体质量指数(BMI)、妊娠24~27+6周75 g OGTT结果均正常的孕妇422例为研究对象,至28~36周时,体质量增长≥4000 g(体质量增速≥500 g/w)的病例为研究组(103例),4000 g(体质量增速500 g/w)的为对照组(319例),采用成组t检验或χ~2检验比较两组孕产妇的妊娠期并发症发生率及围生期结局。结果:研究组GDM(7.8%)、妊娠期高血压(6.8%)、轻度子痫前期(4.9%)、胎膜早破(12.6%)、羊水过多(4.9%)等妊娠期并发症的发生率明显高于对照组(2.8%、2.5%、1.9%、7.2%、1.3%),差异有统计学意义(P0.01);妊娠36周复查OGTT,研究组服糖后2小时血糖、Hb A1c明显高于对照组(P0.01);研究组巨大儿发生率(10.7%)、新生儿出生体质量3677±351 g、新生儿低血糖发生率(4.9%)、剖宫产率(39.8%)均明显高于对照组(6.0%、3328±367 g、2.5%、34.2%),差异有统计学意义(P0.01),两组新生儿阿氏评分差异无统计学意义(P0.05)。结论:妊娠中期OGTT正常的孕妇,如果饮食管理不良,体质量增长过快可能会增加妊娠晚期的并发症的发生率和围生期不良结局。
[Abstract]:Objective: To investigate the pregnancy 75 g oral glucose tolerance (OGTT) and normal late pregnancy body mass growth effects on pregnancy complications and perinatal outcomes. Methods: randomly selected from October 2015 to September 2016 in Second Hospital Affiliated to Tianjin Medical University obstetric examination and before childbirth, pregnancy body mass index (BMI), pregnant 24~27+6 weeks of pregnancy 75 g OGTT results were normal in 422 cases as the research object, to 28~36 weeks, body weight growth of more than 4000 g (body weight growth rate greater than 500 g/w) cases as the study group (103 cases), 4000 g (body weight growth rate of 500 g /w) as the control group (319 Cases), pregnancy complications using t test and X ~2 test between the two groups the incidence of maternal and perinatal outcomes. Results: GDM (7.8%), gestational hypertension (6.8%), mild preeclampsia (4.9%), premature rupture of membranes (12.6%), polyhydramnios (4.9%) and other pregnancy complications. The rate was significantly higher than the control group (2.8%, 2.5%, 1.9%, 7.2%, 1.3%), the difference was statistically significant (P0.01); after 36 weeks of pregnancy study group OGTT, blood glucose 2 hour after Hb, A1c was significantly higher than the control group (P0.01); the study group the incidence of macrosomia, neonatal birth (10.7%) the quality of 3677 + 351 g, the incidence of neonatal hypoglycemia (4.9%), the rate of cesarean section (39.8%) were significantly higher than the control group (6%, 3328 + 367 g, 2.5%, 34.2%), the difference was statistically significant (P0.01), the two groups had no statistically significant difference in Apgar score (P0.05). Conclusion: the second trimester of pregnancy OGTT normal pregnant women, if the diet management bad, excessive growth of body weight may increase in late pregnancy complications and adverse perinatal outcome.

【作者单位】：天津医科大学第二医院;
【分类号】：R714.256

【相似文献】