妇科肿瘤患者输尿管支架相关性尿路感染的病原学分析及耐药性研究

发布时间：2018-04-19 08:43

本文选题：妇科肿瘤 + 尿路感染　；参考：《中国消毒学杂志》2017年05期

【摘要】：目的探讨妇科肿瘤患者留置输尿管支架并发医院尿路感染情况。方法回顾性分析浙江省肿瘤医院2010年1月-2015年6月留置输尿管支架的妇科肿瘤患者尿路感染情况。结果 174例患者中出现尿路感染127例(72.9%),共分离出112株病原菌,其中革兰阴性菌75株(67%),以大肠埃希菌和肺炎克雷伯菌为主;革兰阳性菌35株(31.3%),以粪肠球菌、金黄色葡萄球菌为主;真菌2株(1.8%),均为白色假丝酵母菌。大肠埃希菌对头孢曲松、氨苄西林/舒巴坦、庆大霉素耐药率较高(57.5%~70.3%);肺炎克雷伯菌对呋喃妥因耐药率较高为50%;粪肠球菌对红霉素、庆大霉素、氯洁霉素耐药率较高(61.9%~100%);金黄色葡萄球菌对青霉素G、红霉素、氯洁霉素耐药率较高(50%~75%)。结论留置输尿管支架的妇科肿瘤患者尿路感染率较高,临床应加强感染患者的细菌学监测,根据病原学及药敏结果合理选择抗菌药物,减少耐药株的产生,提高医院感染的治愈率。
[Abstract]:Objective to investigate the nosocomial urinary tract infection in patients with gynecological tumor.Methods the urinary tract infection of gynecological tumor patients with ureteral stents in Zhejiang Cancer Hospital from January 2010 to June 2015 was analyzed retrospectively.Results among 174 patients, 127 patients had urinary tract infection and 112 pathogenic bacteria were isolated, of which 75 were Gram-negative bacteria, mainly Escherichia coli and Klebsiella pneumoniae, 35 Gram-positive strains were Enterococcus faecalis and Staphylococcus aureus.The two fungi were Candida albicans.Escherichia coli showed higher resistance to ceftriaxone, ampicillin / sulbactam, gentamicin, and gentamicin. The resistance rate of Klebsiella pneumoniae to furantoin was 50, and Enterococcus faecalis to erythromycin and gentamicin.The resistance rate of Chloromycin to penicillin G, erythromycin and chloromycin was higher than that of Staphylococcus aureus to penicillin G, erythromycin and chlorchilamycin, and the resistance rate of Staphylococcus aureus to penicillin G, erythromycin and chlortetracycline was higher.Conclusion the urinary tract infection rate of gynecological tumor patients with ureteral stents is higher. The bacteriological monitoring of infected patients should be strengthened and antibiotics should be reasonably selected according to the results of etiology and drug sensitivity in order to reduce the occurrence of drug resistant strains.To improve the cure rate of nosocomial infection.
【作者单位】：浙江省肿瘤医院;
【分类号】：R691.3;R737.3

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