补肾安胎饮联合黄体酮胶丸治疗肾虚型早期先兆流产的临床观察

发布时间：2018-04-20 18:35

本文选题：补肾安胎饮 + 黄体酮胶丸　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：研究目的:中药补肾安胎饮联合西药黄体酮胶丸治疗肾虚型早期先兆流产,通过患者自身症状的前后对比观察,分析中西医结合治疗本病的临床疗效,浅析补肾安胎饮和黄体酮胶丸的作用机理,为临床治疗肾虚型早期先兆流产提供更有效的方案。研究方法:选取2015年4月-2016年10月期间就诊于黑龙江中医药大学附属第一医院妇科门诊,且符合中西医肾虚型早期先兆流产诊断标准的患者36例。所有患者均采用相同的治疗药物,中药汤剂补肾安胎饮(菟丝子20g、桑寄生20g、续断15g、杜仲15g、阿胶珠15g、枸杞15g、白术15g、黄芩15g、苎麻根10g、砂仁10g)150ml,日2次口服;同时口服黄体酮胶丸200mg(2粒),早晚各1次。纳入研究的全部患者自确诊之日起开始药物治疗,14天为一疗程,疗程结束后,采取自身对照比较的研究方法,观察患者治疗前后症状改善情况及临床各项观察指标(母体血清P、E2,B超等),对比分析治疗前后的差异变化。研究结果:36例患者治疗后临床总有效率达94.44%,其中痊愈率和显效率分别为63.89%和22.22%;患者血清P水平显著提高,血清β-HCG和E2水平增长良好;孕12周随访,最终保胎成功率为91.67%。研究结论:补肾安胎饮联合黄体酮胶丸可明确改善肾虚型早期先兆流产患者的临床症状,显著提高患者血清P水平,促进血清β-HCG和E2稳定增长。通过改善妊娠黄体功能,调节母体内分泌水平来提高继续妊娠率。
[Abstract]:Objective: Chinese medicine Bushen Antai drink combined with western medicine Progesterone Soft Capsules in the treatment of Early Threatened Abortion of kidney deficiency type, through the comparison and observation of patients' own symptoms, the clinical effect of combination of traditional Chinese and Western Medicine on the treatment of this disease was analyzed, and the mechanism of the action of Bushen Antai drink and Progesterone Soft Capsules was analyzed to provide more clinical treatment for the Early Threatened Abortion of kidney deficiency type. Methods: the method of study: 36 patients were diagnosed in the Department of gynaecologic outpatient of the First Affiliated Hospital of Heilongjiang University Of Chinese Medicine in April 2015, which was in accordance with the diagnostic standard of Early Threatened Abortion of Chinese and Western kidney deficiency. All the patients were treated with the same medicine, the decoction of Chinese medicine (20g of dodder, 20g, 20g, continued). Break 15g, Eucommia 15g, gelatin bead 15g, wolfberry 15g, Rhizoma Atractylodes 15g, Radix Scutellariae 15g, ramie root 10g, Amomum 10g) 150ml, 2 times a day orally; at the same time, oral Progesterone Soft Capsules 200mg (2 grains), 1 times each in the morning and evening. The improvement of the symptoms and the clinical observation indexes (maternal serum P, E2, B ultrasound and so on) before and after treatment were examined. The results were compared and analyzed before and after treatment. The total clinical effective rate of 36 patients was 94.44%, of which the recovery rate and effective rate were 63.89% and 22.22%, the serum P level was significantly improved, serum beta -HCG and E2 water were increased. After 12 weeks of pregnancy, after 12 weeks of pregnancy, the final success rate of fetus preservation was the conclusion that the combination of Bushen Antai drink combined with Progesterone Soft Capsules could improve the clinical symptoms of the patients with Early Threatened Abortion of kidney deficiency, improve the serum P level, promote the stable growth of serum beta -HCG and E2, and regulate the endocrine water of the mother body by improving the function of the corpus luteum of pregnancy. To improve the rate of continued pregnancy.

【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R714.21

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