MRI参数预测超声消融子宫肌瘤效果的初步研究
发布时间:2018-04-20 18:03
本文选题:磁共振参数 + 预测分析 ; 参考:《重庆医科大学》2014年硕士论文
【摘要】:目的:探讨治疗前子宫肌瘤MRI参数对预测超声消融治疗子宫肌瘤消融疗效的价值。 资料和方法:回顾性分析中国科学院上海临床中心/上海市徐汇区中心医院影像科超声消融治疗中心2012年4月至2013年12月94例患者152个子宫肌瘤进行超声引导HIFU消融治疗的资料数据,通过对治疗前靶肌瘤的MRI T2信号强度值、T2信号强度比值及其信号均匀度、弥散加权成像ADC值和血供类型进行分析,评估磁共振参数数值和超声消融治疗效果的关系,设定其阈值并分组,,比较分析各组与治疗后肌瘤消融率的关系。 结果:T2信号强度阈值为200,≥200和<200的肌瘤的平均消融率分别为81.3±16.8%、90±13.7%(P<0.05);T2信号强度比值的阈值为1.5,≥1.5和<1.5肌瘤的平均消融率分别为83.6±17.2%、89.7±13.3%(P<0.05);扩散加权成像ADC值的阈值为1.4×10-3mm2/s,其≥1.4×10-3mm2/s和<1.4×10-3mm2/s肌瘤的平均消融率分别为81.7±18.4%、88.3±14.3%(P<0.05)。血供丰富、少血供类型肌瘤的平均消融率分别为80.8±18.8%、89.8±12.8%(P<0.05);血供丰富类型伴T2信号强度比值≥1.5肌瘤的平均消融率低于少血供类型伴T2信号强度比值<1.5、少血供类型伴T2信号比值≥1.5、血供丰富类型伴T2信号比值<1.5的肌瘤(P<0.05);T2均匀高信号肌瘤的平均消融率低于T2不均匀高信号、T2均匀低信号、T2不均匀低信号的肌瘤(P<0.05)。 结论:T2信号及其均匀度、ADC值和血供类型磁共振影像参数可预测聚焦超声治疗子宫肌瘤的消融疗效,T2均匀高信号和血供丰富的肌瘤超声消融率较低。
[Abstract]:Objective: to evaluate the value of MRI parameters in predicting the effect of ultrasound ablation on uterine leiomyoma before treatment. Materials and methods: a retrospective analysis of 152 uterine leiomyomas with ultrasound guided HIFU was performed in 94 patients with uterine leiomyoma from April 2012 to December 2013 in Shanghai Clinical Center of Chinese Academy of Sciences / Center Hospital of Xuhui District of Shanghai. Data on ablation treatment, By analyzing the MRI T2 signal intensity ratio and signal uniformity, diffusion-weighted imaging ADC value and blood supply type of target leiomyoma before treatment, the relationship between magnetic resonance parameters and the effect of ultrasound ablation was evaluated. The relationship between each group and the ablation rate of leiomyoma after treatment was compared and analyzed. Results the mean ablation rate of myoma with T 2 signal intensity threshold of 200, 鈮
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