胎膜早破与生殖道感染的相关性探讨

发布时间：2018-04-22 19:01

本文选题：胎膜早破 + 感染　；参考：《中国计划生育学杂志》2016年01期

【摘要】：目的:探讨胎膜早破与感染的相关性。方法:回顾性分析2014年6月~2015年5月本院妇产科住院分娩的胎膜早破孕妇200例资料(观察组),选取同期妇产科住院分娩的非胎膜早破孕妇200例作为对照组,分别对两组的入院血常规(包括血白细胞计数)、C-反应蛋白、阴道分泌物做白带常规(含阴道清洁度测定)、细菌培养、细菌性阴道病(BV)检测、宫颈分泌物检测沙眼衣原体(UU)及解脲支原体(CT)资料进行分析。结果:观察组CRP及白细胞值均高于对照组(t=17.80、12.45,均P0.01);胎膜早破感染者CRP显著高于胎膜早破非感染者(t=35.73,P0.01)。观察组UU、CT、BV、白色念珠菌、滴虫及混合感染的发生率均高于对照组(χ~2=11.706,12.732,5.530,13.636,8.163,13.636,均P0.05),生殖道感染率观察组(70%)高于对照组(30%)(χ~2=64.000,P0.05)。观察组新生儿早产、新生儿肺炎、新生儿窒息及孕妇产褥感染及产后出血的发生率均高于对照组(χ~2=29.249,24.242,35.470,9.338,9.421,均P0.05)。结论:胎膜早破与生殖道感染存在相关性,CT、UU、白色念珠菌为主要的病原体。因此妇女在计划妊娠前,首先要到医院进行生殖道病原学检查,及时发现感染并于孕前彻底治疗以降低胎膜早破及早产发生率,减少羊膜腔感染,降低母婴病率,提高围产保健质量。
[Abstract]:Objective: To investigate the correlation between premature rupture of fetal membranes and infection. Methods: a retrospective analysis of 200 pregnant women with premature rupture of membranes in obstetrics and gynecology in May, ~2015, June 2014, and 200 cases of non fetal premature rupture in obstetrics and gynecology as control group were selected as the control group, and the admission blood routine (including blood leukocyte meter) in two groups was taken respectively. C- reactive protein, vaginal secretions for leukorrhea routine (including vaginal cleanliness test), bacterial culture, bacterial vaginosis (BV), cervical secretions for detection of Chlamydia trachomatis (UU) and Ureaplasma urealyticum (CT). Results: the values of CRP and leukocyte in the observation group were higher than those of the control group (t=17.80,12.45, P0.01), and C of premature rupture of membranes. RP was significantly higher than that of premature rupture of membrane (t=35.73, P0.01). The incidence of UU, CT, BV, Candida albicans, trichomonas and mixed infection in the observation group were higher than that of the control group (x ~2=11.706,12.732,5.530,13.636,8.163,13.636, P0.05), the rate of reproductive tract infection (70%) was higher than that of the control group (30%) (x ~2=64.000, P0.05). The incidence of infant pneumonia, neonatal asphyxia, puerperal infection and postpartum hemorrhage of pregnant women were higher than those of the control group (x ~2=29.249,24.242,35.470,9.338,9.421, P0.05). Conclusion: there is a correlation between premature rupture of membranes and genital tract infection, CT, UU, Candida albicans are the main pathogens. Aetiology examination, timely detection of infection and thorough treatment before pregnancy can reduce the incidence of premature rupture of membranes and premature delivery, reduce amniotic cavity infection, reduce the rate of maternal and infant disease, and improve the quality of perinatal health care.

【作者单位】：温州医科大学;温州医科大学附属第一医院产科;浙江省温州市鹿城区人民医院妇产科;
【基金】：温州市卫生局资助项目(2015B26)
【分类号】：R714.433

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