多功能醋酸白溶液在宫颈病变筛查中的应用价值

发布时间：2018-04-30 12:42

本文选题：宫颈病变 + 多功能醋酸白溶液　；参考：《现代妇产科进展》2015年07期

【摘要】：目的:评价多功能醋酸白溶液在宫颈病变筛查中的应用价值。方法:对2012年11月至2014年12月在上海交通大学医学院附属仁济医院和上海中医药大学附属曙光医院妇科门诊的361例就诊患者进行宫颈病变筛查。采取患者的宫颈脱落细胞行薄层液基细胞学(TCT)检测,然后应用多功能醋酸白溶液进行宫颈染色肉眼观察试验,最后预约时间行阴道镜及活检病理检查。结果:多功能醋酸白染色法和TCT法与阴道镜下活检的阳性符合率分别为29.98%、26.59%,阴性符合率分别为64.27%、65.65%,差异均无统计学意义(P0.05)。多功能醋酸白染色法与TCT法的异常细胞检出率(32.41%和30.75%)、正常细胞检出率(40.17%和43.49%)、炎症检出率(27.42%和25.76%)、CIN II检出率(12.74%和8.31%)、CIN III或癌检出率(8.03%和5.54%)比较,差异均无统计学意义(P0.05);而CIN I检出率(11.63%和16.90%)比较,差异则有统计学意义(P0.05)。结论:多功能醋酸白溶液肉眼观察试验筛查宫颈病变的价值较高,因其方便快捷、价格低廉、敏感性高,在经济不发达地区或低收入人群中有较高的应用价值,配合阴道镜下活检对早期宫颈病变是一种有用的筛选方法。
[Abstract]:Objective: to evaluate the value of multifunctional white acetate solution in screening cervical lesions. Methods: from November 2012 to December 2014 361 patients from Renji Hospital affiliated to Shanghai Jiaotong University and Shuguang Hospital affiliated to Shanghai University of traditional Chinese Medicine were screened for cervical lesions. The cervical exfoliated cells of the patients were detected by thin layer liquid based cytology (TCTT), then the colposcopy and pathological examination were performed by colposcopy and biopsy with multifunctional acetic acid white solution. Results: the positive coincidence rates of multifunctional white acetate staining, TCT and colposcopy biopsy were 29.98 and 65.65, respectively, and the negative coincidence rates were 64.27 and 65.65, respectively. The difference was not statistically significant (P 0.05). The detection rates of abnormal cells were 32.41% and 30.75% by multifunctional acetic acid white staining, 40.17% and 43.49% of normal cells, and 27.42% and 25.76% of cin II, respectively. The detection rates of cin III or cancer were 8.03% and 5.54%, respectively. There was no significant difference (P 0.05), but the detection rate of CIN I was 11.63% and 16.90% respectively. Conclusion: the multifunctional white acetic acid solution can be used to screen cervical lesions because of its convenience, low cost and high sensitivity, and has high value in economic underdeveloped areas or low-income population. Colposcopy biopsy is a useful screening method for early cervical lesions.
【作者单位】：上海中医药大学附属曙光医院妇产科;
【分类号】：R737.33

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