无锡地区孕妇弓形虫感染及危险因素调查

发布时间：2018-05-01 14:31

本文选题：弓形虫感染 + 孕妇　；参考：《中国血吸虫病防治杂志》2015年06期

【摘要】：目的调查江苏省无锡市孕妇弓形虫感染情况及其危险因素,为制定预防控制孕妇弓形虫感染措施提供参考依据。方法 2011-2014年采用酶联免疫吸附试验(ELISA)对3 014例孕妇进行抗弓形虫Ig M和Ig G抗体检测并追踪随访,观察其妊娠结局;采用问卷调查孕妇弓形虫感染的危险因素。结果 3 014例被调查的孕妇中,弓形虫抗体检测阳性215例,抗体阳性率为7.13%,其中Ig M抗体阳性49例(占22.79%),Ig G抗体阳性166例(占77.21%)。随访结果表明,215例感染弓形虫的孕妇中46例出现不良妊娠结局(占21.40%),其中35例Ig M抗体阳性(76.09%),11例Ig G抗体阳性(23.91%)。275例未感染弓形虫孕妇中,7例出现不良妊娠结局(占2.55%)。弓形虫感染和未感染孕妇不良妊娠结局发生率差异有统计学意义(P0.01)。单因素分析显示,与动物密切接触、喜吃生肉、喜吃火锅或烧烤、品尝生肉馅等是孕妇感染弓形虫的重要危险因素(与未感染组比较,P0.01)。结论孕妇弓形虫感染可导致不良妊娠结局的发生,减少动物密切接触、养成良好的饮食卫生习惯以及做好孕期弓形虫感染监测工作等是避免不良妊娠结局的有效途径。
[Abstract]:Objective to investigate the situation and risk factors of toxoplasma gondii infection among pregnant women in Wuxi, Jiangsu Province, and to provide reference for the prevention and control of toxoplasma gondii infection among pregnant women. Methods from 2011 to 2014, 3014 pregnant women were tested for antibodies against Toxoplasma gondii Ig M and IgG by Elisa and followed up to observe their pregnancy outcome, and the risk factors of Toxoplasma gondii infection were investigated by questionnaire. Results among 3 014 pregnant women surveyed, 215 cases were positive for Toxoplasma gondii antibody, and the positive rate of antibody was 7.13. Among them, 49 cases were positive for IgG antibody, 166 cases were positive for IgG antibody (77.21 1%). The follow-up results showed that 46 out of 215 pregnant women infected with Toxoplasma gondii had adverse pregnancy outcomes (21.40%), among which 35 cases were positive for IgM antibody and 76.09 9 for 11 cases. Among 275 cases of uninfected pregnant women with Toxoplasma gondii infection, 7 cases had adverse pregnancy outcome (2.55%). There were significant differences in the incidence of adverse pregnancy outcomes between pregnant women infected with Toxoplasma gondii and those without infection (P 0.01). Univariate analysis showed that close contact with animals, preferring to eat raw meat, hot pot or barbecue, and tasting raw meat filling were the important risk factors of infection of Toxoplasma gondii in pregnant women (compared with uninfected group). Conclusion Toxoplasma gondii infection in pregnant women can lead to adverse pregnancy outcomes, reduce close contact with animals, develop good diet and hygiene habits, and do a good job of monitoring toxoplasma infection during pregnancy are effective ways to avoid adverse pregnancy outcomes.
【作者单位】：江苏省无锡市第九人民医院;
【分类号】：R714.25

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