220例绝经后妇女宫颈癌筛查结果分析

发布时间：2018-05-01 18:52

  本文选题：宫颈癌 + 人乳头瘤病毒　； 参考：《山东医药》2015年24期

【摘要】：目的分析220例绝经后妇女人乳头瘤病毒(HPV)感染情况及基因型别。方法采集2013年3~7月在天津市南开区参加宫颈癌筛查的220例绝经后妇女的宫颈细胞学标本,采用液基薄层细胞学检查(TCT)检测细胞学结果,利用PCR及焦磷酸测序技术检测HPV DNA并分型。结果共检测HPV DNA阳性21例(9.55%),检出9种HPV。其中,高危型HPV感染19例(HPV16 9例),低危型HPV感染3例,包含混合感染1例。TCT显示,正常/炎症者214例,细胞学结果异常者6例;在正常/炎症者中HPV DNA阳性15例(7.00%),细胞学异常者HPV DNA均阳性(100%)。对6例TCT结果≥ASCUS者宫颈活检病理检查显示,慢性宫颈炎4例,CINⅠ级1例,CINⅡ级1例。结论绝经后妇女仍有一定的HPV感染率,其中HPV16是最常见的型别,绝经后妇女仍需注重妇科查。
[Abstract]:Objective to analyze the infection and genotype of human papillomavirus (HPV) in 220 postmenopausal women. Methods the cervical cytological specimens of 220 postmenopausal women who took part in cervical cancer screening in Nankai District of Tianjin from March to July 2013 were collected and the cytological results were detected by liquid based thin layer cytology (TCTs). HPV DNA was detected and typed by PCR and pyrosequencing. Results A total of 21 cases with HPV DNA positive were detected and 9 kinds of HPVs were detected. Among them, there were 19 cases of high risk HPV infection and 3 cases of low risk HPV infection, including 1 case of mixed infection, 214 cases of normal / inflammatory infection and 6 cases of abnormal cytological results. In normal / inflammatory patients, HPV DNA was positive in 15 cases and HPV DNA was positive in all cases with abnormal cytology. The pathological examination of cervical biopsy in 6 cases with TCT 鈮，

本文编号：1830637