羊膜联合大黄、芒硝促进切口愈合的临床研究

发布时间：2018-05-11 18:31

  本文选题：羊膜 + 大黄　； 参考：《新乡医学院》2014年硕士论文

【摘要】：背景：近年来如何做到术后减轻疼痛甚至无瘢痕愈合愈来愈受妇产科医生的重视。中药成分紫河车主要来自胎盘中的胎膜,在促进上皮干细胞及毛细血管再生、减少瘢痕中重要成分纤维化因子形成等各方面有重要作用。大黄配伍芒硝在促进剖宫产皮肤切口愈合中的作用已被认可,能促进切口愈合。羊膜与大黄、芒硝两者联合在切口愈合中的应用目前在国内外鲜见报道,本研究将探讨羊膜联合大黄、芒硝促进剖宫产皮肤切口愈合的重要疗效。 目的：研究剖宫产皮肤切口不同处理方法,利用术后切口疼痛、肿胀程度,瘢痕形成程度、切口愈合等级综合判断剖宫产切口愈合情况,探讨羊膜联合大黄、芒硝促进剖宫产切口愈合的疗效 方法：选择2011年1月-2012年10月在濮阳市油田总医院产科行择期剖宫产分娩的健康产妇共400人,随机分为4组,每组100人。所有病人皮肤切口仅缝合皮下组织,不缝合皮肤。研究1组术毕切口外敷自体羊膜,术后1天联合大黄、芒硝外敷切口直至术后5天；研究2组术毕皮肤切口外敷自体羊膜,术后常规换药；研究3组术毕皮肤切口常规包扎,术后1天切口外敷大黄、芒硝直至术后5天；对照4组术毕皮肤切口常规包扎,术后常规换药。 结果： 1.研究1组、2组、3组与对照4组相比,术后瘢痕形成显著者所占比例明显降低,但只有研究1组与对照组差异有统计学意义(P0.05)；研究1组与研究2组、3组比较,差异无统计学意义(P0.05)；研究2组与研究3组相比较,单独应用自体羊膜或大黄、芒硝对降低瘢痕形成的差异不显著,不具有统计学意义(P0.05)； 2.研究1组随访中均为甲级愈合,其余三组组均存在数例乙级愈合,四组均无丙级愈合。研究1组与各组比较均有统计学意义(P0.05)；研究2组、3组与对照组比较有差异(P0.05)；但研究2组、3组间剖宫产皮肤切口愈合等级程度影响差异无统计学意义（P0.05)。 3.四组重度疼痛均为0例。研究1组与各组相比,明显降低剖宫产皮肤切口疼痛程度。研究2组、3组与对照组比较有显著差异(P0.05)；单独应用羊膜组相比较于单独应用大黄、芒硝组剖宫产切口疼痛程度降低,差异具有统计学意义(P0.05)。 4.四组中均评分3分均为0例。研究1组与各组相比,明显降低剖宫产皮肤切口肿胀程度。研究2组、3组与对照组比较有显著差异(P0.05)；单独应用大黄、芒硝组比单独应用羊膜组切口肿胀程度降低,差异具有统计学意义(P0.05)。 结论：羊膜联合大黄、芒硝外敷切口显著降低剖宫产皮肤切口疼痛、肿胀、瘢痕形成程度,有利于切口愈合。
[Abstract]:Background: in recent years, how to reduce pain and even without scar healing has been paid more and more attention by obstetricians and obstetricians. The Chinese medicine component Purple River car mainly comes from the fetal membrane in the placenta. It plays an important role in promoting the regeneration of epithelial stem cells and capillaries and reducing the important component of fibrotic factor in scar. The effect of the combination of amniotic membrane and rhubarb and Mirabilite in the healing of incisional incision is rarely reported at home and abroad. This study will discuss the important effect of amniotic membrane combined with rhubarb and mirabilite to promote the healing of incision of caesarean section.
Objective: To study the different treatment methods of caesarean section skin incision, use the postoperative incision pain, swelling degree, scar formation degree and incision healing grade to synthetically judge the healing of cesarean section, and discuss the effect of amniotic membrane combined with rhubarb and mirabilite to promote cesarean section healing.
Methods: a total of 400 healthy parturient women who were selected for cesarean section in the obstetrics department of Puyang oil field general hospital, January 2011, were randomly divided into 4 groups, 100 people in each group. The skin incision was only sutured and the skin was not sutured in all patients. The 1 groups were applied with autogenous amniotic membrane on the 1 groups, and 1 days after the operation, the incisions of mirabilite were applied straight to the incision. To the 5 day after the operation, the 2 groups were treated with autogenous amniotic membrane on the skin incision and conventional dressing after operation; the 3 groups were treated with routine dressing on the skin incision, 1 days after the operation with rhubarb and 5 days after the operation, and the 4 groups were treated with routine dressing after the skin incision and routine dressing change after operation.
Result锛，

本文编号：1875081