寨卡病毒单一位点突变显著增加胎儿罹患小头症风险

发布时间：2018-05-15 06:21

  本文选题：小头 + 胎儿　； 参考：《中国科学:生命科学》2017年11期

【摘要】：正寨卡病毒因其于1947年被首次分离自乌干达的寨卡森林而得名.其后数十年,由于寨卡病毒在人群中的偶发感染及所致的温和病症,一直不太为人所知.直到2015年寨卡病毒在巴西乃至全球大流行,并导致部分胎儿及新生儿罹患先天性脑畸形,如小头症等~([1,2]),引起了整个人类社会的密切关注,被世界卫生组织在2016年2月定义为"全球紧急公共卫生事件".此前已有研究表明,寨卡病毒是通过靶向作用于
[Abstract]:Zheng Zika virus was first isolated from Uganda's Zika forest in 1947. Fortuitous infections and mild symptoms of Zika have been unknown for decades. Until 2015, when the Zika virus became prevalent in Brazil and even the world, causing some foetus and newborns to develop congenital brain deformities, such as microcephaly ([1] /), it attracted close attention from the entire human society. It was defined by the World Health Organization in February 2016 as a global public health emergency. Previous studies have shown that the Zika virus is targeted
【作者单位】： 中国医学科学院系统医学研究中心;苏州系统医学研究所;
【分类号】：R714.5
，

本文编号：1891331