扩散加权成像评价胎儿轻度侧脑室扩张

发布时间：2018-05-27 22:03

本文选题：扩散磁共振成像 + 表观扩散系数　；参考：《中国医学影像技术》2017年05期

【摘要】：目的探讨ADC值对胎儿轻度侧脑室扩张的诊断价值。方法对15胎轻度侧脑室扩张胎儿(侧脑室扩张组)及15胎侧脑室无扩张的胎儿(对照组)行DWI扫描,测量双侧额叶、顶叶、颞叶、枕叶白质、基底核、丘脑及小脑ADC值,比较2组各脑区ADC值差异及轻度侧脑室扩张胎儿左侧及右侧各脑区ADC值的差异。分析所有胎儿各脑区ADC值与孕周的相关性、侧脑室扩张胎儿侧脑室宽度与孕周的相关性。结果与对照组比较,轻度侧脑室扩张组双侧额叶、双侧顶叶白质ADC值下降(P均0.05)。侧脑室扩张胎儿左侧与右侧各脑区ADC值差异均无统计学意义(P均0.05)。相关分析显示所有胎儿双侧枕叶、双侧基底核区、双侧丘脑、双侧小脑及左侧颞叶ADC值与孕周呈负相关,侧脑室扩张胎儿侧脑室宽度与孕周呈正相关(r=0.635,P=0.011)。结论轻度侧脑室扩张胎儿额叶、顶叶ADC值下降,ADC值对检测潜在脑部损伤较敏感,有助于诊断胎儿侧脑室扩张。
[Abstract]:Objective to investigate the diagnostic value of ADC value in mild lateral ventricular dilatation of fetus. Methods DWI scanning was performed on 15 infants with mild ventricular dilatation (lateral ventricular dilatation group) and 15 fetus without ventricular dilatation (control group). The ADC values of bilateral frontal lobe, parietal lobe, temporal lobe, white matter of occipital lobe, basal nucleus, thalamus and cerebellum were measured. The differences of ADC values in different brain regions and ADC values in left and right brain regions of mild lateral ventricular dilatation fetus were compared between the two groups. The correlation between ADC values and gestational weeks in all fetal brain regions was analyzed, and the correlation between the width of lateral ventricle and gestational weeks in dilated foetal ventricles was analyzed. Results compared with the control group, the white matter ADC of the bilateral frontal lobe and parietal lobe in the mild ventricular dilatation group were decreased (P < 0.05). There was no significant difference in ADC between left and right brain regions of the fetus with lateral ventricular dilatation (P < 0.05). Correlation analysis showed that the ADC values of bilateral occipital lobe, bilateral basal nucleus, bilateral thalamus, bilateral cerebellum and left temporal lobe were negatively correlated with gestational weeks in all fetuses. Conclusion the decrease of ADC value in the parietal lobe is sensitive to the detection of potential brain injury, which is helpful to the diagnosis of fetal lateral ventricular dilatation.
【作者单位】：北京大学第三医院放射科;
【分类号】：R445.2;R714.5

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