子宫内膜异位症患者血清中Syndecan-1的表达及意义
发布时间:2018-05-28 14:00
本文选题:子宫内膜异位症 + 可溶性多配体蛋白聚糖- ; 参考:《广东医学》2015年02期
【摘要】:目的探讨Syndecan-1在子宫内膜异位症(内异症)患者中的表达水平和临床分期中的意义。方法采用ELISA法对88例内异症患者(观察组)和35例同期因良性子宫肌瘤住院手术的患者(对照组)血清中Syndecan-1的表达水平进行检测,并对内异症分期进行相关性分析。结果观察组患者血清中的Syndecan-1表达水平明显高于对照组(P0.05),Ⅲ、Ⅳ期内异症患者血清中Syndecan-1的表达水平较Ⅰ、Ⅱ期患者明显升高,差异有统计学意义(P0.05)。结论 Syndecan-1在内异症血清中表达水平较高,可能参与了内异症的发病机制,可考虑成为内异症诊断的指标之一,并且根据Syndecan-1的表达水平来预测内异症临床分期。
[Abstract]:Objective to investigate the expression level and clinical stage of Syndecan-1 in patients with endometriosis (endometriosis). Methods the expression of Syndecan-1 in 88 patients with endometriosis (observation group) and 35 patients with benign uterine leiomyoma (control group) were detected by ELISA method, and the correlation between the stage of endometriosis and the stage of endometriosis was analyzed. Results the expression of Syndecan-1 in the serum of the patients in the observation group was significantly higher than that in the patients with stage 鈪,
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