联合用药治疗妊娠合并支原体衣原体感染的疗效

发布时间：2018-05-29 14:28

本文选题：阿奇霉素 + 头孢呋辛　；参考：《热带医学杂志》2016年12期

【摘要】：目的探讨阿奇霉素联合头孢呋辛治疗妊娠合并支原体衣原体感染的临床效果,为临床药物治疗提供依据。方法选取2015年1月至2016年1月于海口市妇幼保健院接受治疗的妊娠合并支原体衣原体感染孕妇400例。患者按入院先后顺序随机分为观察组(n=200)与对照组(n=200),对照组给予阿奇霉素治疗,观察组在对照组基础上联用头孢呋辛治疗。结果观察组治疗有效率为100.00%,明显高于对照组的68.50%,差异有统计学意义(P0.05)。治疗后,观察组不良反应发生率为12.50%,对照组不良反应发生率为11.50%,两组不良反应差异无统计学意义(P0.05)。观察组胎膜早破、产褥感染、低体重儿发生率明显低于对照组(P0.05)。结论阿奇霉素联合头孢呋辛治疗妊娠合并支原体衣原体感染的临床效果显著,有利于改善妊娠结局,且不良反应发生率低。
[Abstract]:Objective to investigate the clinical effect of azithromycin combined with cefuroxime in the treatment of pregnant women with chlamydia mycoplasma infection. Methods 400 pregnant women with mycoplasma chlamydia infection were selected from January 2015 to January 2016 in Haikou Maternal and Child Health Hospital. The patients were randomly divided into observation group (n = 200) and control group (n = 200). The control group was treated with azithromycin, and the observation group was treated with cefuroxime on the basis of the control group. Results the effective rate of treatment was 100.00g in the observation group, which was significantly higher than that in the control group (68.50%). The difference was statistically significant (P 0.05). After treatment, the incidence of adverse reactions was 12.50 in the observation group and 11.50 in the control group. There was no significant difference in the adverse reactions between the two groups (P 0.05). The incidence of premature rupture of membranes, puerperal infection and low birth weight in the observation group was significantly lower than that in the control group (P 0.05). Conclusion Azithromycin combined with cefuroxime in the treatment of pregnancy with chlamydia infection is effective and beneficial to improve the outcome of pregnancy, and the incidence of adverse reactions is low.
【作者单位】：海口市妇幼保健院药剂科;海口市妇幼保健院保健部;
【分类号】：R714.251

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