孕期不同阶段增重与新生儿出生体重的相关性

发布时间：2018-06-01 08:49

本文选题：孕前体重指数 + 孕期增重　；参考：《现代妇产科进展》2017年05期

【摘要】：目的:探讨正常足月孕妇孕期不同阶段增重与新生儿出生体重的关系。方法:回顾分析2014年1月至2014年12月在嵊州人民医院定期产前检查并且正常足月单胎孕妇2634例的临床资料。根据孕前体重指数(BMI)分为3组:低体重组(18.5kg/m2),正常体重组(18.5~23.9kg/m2),超重组(24~27.9kg/m2)。收集孕妇早、中、晚孕期的体重增加值,分析孕期不同阶段增重与新生儿出生体重的关系。结果:低体重组、正常体重组和超重组孕期增重分别为15.0kg(12.7,17.7kg)、14.5kg(12.0,17.5kg)和13.0kg(9.0,16.0kg);新生儿出生体重分别为3230g(3000,3470g)、3330g(3090,3600g)和3437g(3140,3722g),3组比较差异均有统计学意义(P0.05)。低体重组、正常体重组和超重组早孕期增重分别为1.4kg(0.6,2.3kg)、1.1kg(0.6,2.1kg)和1.1kg(0.4,1.9kg);中孕期增重分别为7.8kg(6.5,9.4)kg、7.5kg(6.0,9.0kg)和6.5kg(4.8,8.1kg);晚孕期增重分别为5.8kg(4.2,7.5kg)、5.7kg(4.2,7.4kg)和5.1kg(3.5,7.0kg);同孕期3组比较,差异均有统计学意义(P0.05)。回归结果表明,除低体重组晚孕期和超重组早孕期以外,其余各孕期体重增加对新生儿出生体重均有促进作用。其中低体重组早孕期增重对新生儿体重增加影响最大(标准化回归系数0.21,P0.05);正常体重组和超重组中孕期增重对新生儿体重增加影响最大(标准化回归系数分别为0.18,0.10,P均0.05)。含哑变量的回归结果示,对整个研究群体而言,中孕期增重对出生体重的影响最大(标准化回归系数0.18,P0.05);相对于正常体重组早孕期增重对新生儿出生体重增加的影响而言,低体重组孕早期增重影响更大(标准化回归系数差为0.05,P0.05),而超重组最小(标准化回归系数差为-0.06,P0.05)。结论:孕前BMI和孕期不同阶段增重与新生儿出生体重有关;低体重组早孕期增重对新生儿出生体重增加影响最明显,而正常体重组和超重组则中孕期增重对新生儿体重增加最明显。因此,根据孕前BMI制定孕期不同阶段合理增重对于控制新生儿体重具有指导意义。
[Abstract]:Objective: to investigate the relationship between birth weight gain and birth weight of normal term pregnant women at different stages of pregnancy. Methods: the clinical data of 2634 pregnant women with normal term single pregnancy from January 2014 to December 2014 in Shengzhou people's Hospital were retrospectively analyzed. BMIs were divided into three groups: low weight group (18.5kg / m2), normal weight group (18.5kg / m2), hyperrecombination group (2427.9 kg / m2). To collect the weight gain of pregnant women in early, middle and late pregnancy, and to analyze the relationship between birth weight and birth weight in different stages of pregnancy. Results: in low body weight group, normal body weight group and super reconstituted pregnancy weight gain group were 15.0 kg / kg 12.7kg / 17.7 kg / kg and 13.0kg / 9.0kg / kg respectively, and the birth weight of newborns were 3230g / 3000g / 3470g / kg ~ 3330g / 30903600g) and 3437g / 3140g / 3722g / g respectively. In the low body weight group, the weight gain in the normal body weight group and the superrecombinant early pregnancy group were 1.4 kg 路kg ~ (0.6) and 2.3kg ~ (2. 3) kg ~ (-1) 路kg ~ (-1)? The results of regression analysis showed that, except for the late pregnancy and the superrecombinant early pregnancy in the low weight group, the weight gain during the other pregnancy had a positive effect on the birth weight of the newborn. In the low weight group, the weight gain in early pregnancy had the greatest effect on the newborn weight gain (standardized regression coefficient was 0.21%, P 0.05), and the weight gain in normal weight group and over recombination group had the greatest effect on the newborn weight gain (the standardized regression coefficient was 0.18 ~ 0.10) (P < 0.05). Regression results with dummy variables showed that weight gain during pregnancy had the greatest effect on birth weight for the whole study population (standardized regression coefficient 0.18, P 0.05), compared with the effect of weight gain during early pregnancy on birth weight gain in normal weight group. In low body weight group, the effect of weight gain was greater (the difference of standardized regression coefficient was 0.05p 0.05, and the difference of standard regression coefficient was -0.06g P 0.05). Conclusion: BMI before pregnancy and weight gain at different stages of pregnancy are related to the birth weight of the newborn, and the weight gain in the early pregnancy of low weight group has the most obvious effect on the birth weight gain of the newborn. In normal weight group and hyperrecombination group, weight gain during pregnancy was the most significant in newborns. Therefore, reasonable weight gain in different stages of pregnancy according to BMI before pregnancy is of guiding significance for the control of neonatal weight.
【作者单位】：浙江大学医学院附属妇产科医院;嵊州市人民医院;
【基金】：浙江省卫计委科研项目和省部共建项目资助(No:2014KYA248和WKJ-ZJ-1722) 国家自然科学基金资助(No:81370725)
【分类号】：R714

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