高强度聚焦超声治疗子宫肌瘤初始学习曲线分析

发布时间：2018-06-02 03:12

本文选题：高强度聚焦超声消融 + 子宫肌瘤　；参考：《中国介入影像与治疗学》2015年03期

【摘要】：目的探讨高强度聚焦超声(HIFU)治疗子宫肌瘤的学习曲线。方法前瞻性研究分析同一组3名接受超声消融培训的医师完成的最初60例HIFU治疗子宫肌瘤手术,按手术日期的先后,将60例患者的临床资料分为A、B和C组,每组20例。分析随手术例数的累积,治疗时间、照射时间、治疗强度、肌瘤消融率和患者不良反应是否存在学习曲线。结果 A组治疗时间明显长于C组(P=0.033);A组照射时间明显长于B、C组(P=0.041、0.038);三组治疗强度、消融率差异无统计学意义(P0.05)。全部病例无严重并发症发生,不良反应并未随着手术例数的增加有明显改变。治疗时间和照射时间存在学习曲线。结论 HIFU治疗子宫肌瘤存在学习曲线。在40例的操作经验后,治疗时间和照射时间明显缩短,消融率逐渐上升。培训期间,在指导老师监督下的操作是安全的。
[Abstract]:Objective to explore the learning curve of high intensity focused ultrasound (HIFU) in the treatment of uterine leiomyoma. Methods A prospective study was carried out in the same group of 3 physicians who received ultrasound ablation training for the treatment of uterine leiomyoma in the first 60 cases. According to the date of operation, 60 cases were divided into two groups: group A (n = 20) and group C (n = 20). To analyze whether there is a learning curve with the number of patients, the time of treatment, the time of irradiation, the intensity of treatment, the ablation rate of myoma and the adverse reactions of patients. Results the time of treatment in group A was longer than that in group C (P 0.033), and the time of irradiation in group A was significantly longer than that in group B (P < 0.01), but there was no significant difference in treatment intensity and ablation rate among the three groups (P 0.05). No serious complications occurred in all cases, and adverse reactions did not change significantly with the increase in the number of cases. There was a learning curve between the time of treatment and the time of irradiation. Conclusion HIFU has a learning curve in the treatment of uterine leiomyoma. After the operation of 40 cases, the treatment time and irradiation time were shortened obviously, and the ablation rate increased gradually. During the training period, the operation under the supervision of the instructor is safe.
【作者单位】：重庆医科大学生物医学工程学院省部共建国家重点实验室培育基地——重庆市超声医学工程重点实验室重庆市生物医学工程学重点实验室;重庆医科大学附属第一医院超声消融治疗中心;
【基金】：“十二五”国家科技支撑计划项目(2011BAI14B01) 973项目(2011CB707900;2012CB722402) 2011年高等学校博士学科点专向科研基金联合资助课题(20115503110014)
【分类号】：R737.33

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