薄型子宫内膜研究进展

发布时间：2018-06-04 19:08

本文选题：薄型子宫内膜 + 定义　；参考：《中国妇产科临床杂志》2017年06期

【摘要】：人类辅助生殖技术日趋成熟,根据临床观察,薄型子宫内膜患者的临床妊娠结局不良。然而究竟多薄的内膜称为薄型子宫内膜,目前尚无定论。其主要高危因素包括高龄、感染、宫腔操作和药物等,但仍存在一部分薄型子宫内膜患者缺乏上述高危因素,称为特发型薄型子宫内膜。目前临床上对于薄型内膜的治疗,主要包括病因治疗、药物治疗、再生医学治疗及中医治疗等。其中集落细胞刺激因子、西地那非、生长激素、他莫昔芬等药物在临床上的使用经验较少,干细胞治疗、富集血小板血浆等再生医学治疗手段仍处于研究阶段,盆底仿生电刺激及中医治疗在部分研究中效果良好。尽管目前对于薄型子宫内膜的治疗方法多种多样,但治疗效果仍不尽满意,期待更为成熟有效的方案,以提高薄型子宫内膜患者的妊娠率及活产率。
[Abstract]:Human assisted reproductive technology is becoming more and more mature. According to clinical observation, the clinical pregnancy outcome of thin endometrium patients is poor. However, how thin the endometrium is called a thin endometrium is still unclear. The main risk factors include old age, infection, uterine cavity operation and drugs, but some of the patients with thin endometrium still lack these high risk factors, which are called special type thin endometrium. At present, the treatment of thin endometrium mainly includes etiological treatment, drug therapy, regenerative medicine treatment and traditional Chinese medicine treatment. Among them, colony stimulating factor, sildenafil, growth hormone, tamoxifen and other drugs in the clinical use of less experience, stem cell therapy, enrichment of platelet plasma and other regenerative medical treatment methods are still in the research stage. Pelvic floor biomimetic electrical stimulation and traditional Chinese medicine treatment in part of the study results. Although there are a variety of treatments for thin endometrium at present, the therapeutic effect is still not satisfactory. We expect a more mature and effective scheme to improve the pregnancy rate and live delivery rate of patients with thin endometrium.
【作者单位】：北京大学人民医院生殖中心;
【分类号】：R714.8

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