宫腔内人工授精临床妊娠率的影响因素分析

发布时间：2018-06-11 15:16

本文选题：人工授精 + 妊娠率　；参考：《中华男科学杂志》2015年11期

【摘要】：目的:分析影响宫腔内人工授精(IUI)临床妊娠率的相关因素。方法:回顾性分析611个周期IUI者的临床资料,探讨女方年龄、不孕年限、不孕类型、所行周期数、周期方案、子宫内膜厚度及形态、处理前精液参数等因素与IUI妊娠率的关系。结果:促排卵周期妊娠率显著高于自然周期(23.03%vs 11.03%,P0.01),第4周期以上的妊娠率较第1、2、3周期明显下降(2.04%vs 21.03%、18.13%、12.67%,P0.01),当女方年龄≥40岁、处理前前向运动精子总数(TPMSC)10×106、前向运动精子百分率20%、正常形态精子百分率2%时,IUI临床妊娠率明显下降(P均0.05)。Logistic回归分析提示周期方案、所行周期数、前向运动精子百分率显著影响IUI临床妊娠率(P0.05)。结论:周期方案、所行周期数、前向运动精子百分率、女方年龄、TPMSC以及精子形态是影响IUI临床妊娠率的重要因素,而不孕年限、不孕类型、子宫内膜厚度及形态对IUI成功率没有明显影响。
[Abstract]:Objective: to analyze the related factors influencing the clinical pregnancy rate of intrauterine artificial insemination (IUI). Methods: the clinical data of 611 patients with IUI were analyzed retrospectively, and the relationship between the pregnancy rate and the pregnancy rate was investigated by analyzing the age of the woman, the years of infertility, the type of infertility, the number of cycles, the thickness and morphology of endometrium, and the parameters of semen before treatment. Results: the pregnancy rate in ovulatory cycle was significantly higher than that in natural cycle (23.03 vs 11.03). The pregnancy rate above the fourth cycle was significantly lower than that in the 1st cycle (2.04 vs 21.03). The total number of forward motile spermatozoa was 10 脳 10 6, the percentage of forward motile sperm was 20, and the clinical pregnancy rate of IUI was significantly decreased at 2 hours after treatment. Logistic regression analysis showed that the cycle scheme and the number of cycles were carried out. The percentage of forward motility sperm significantly affected the clinical pregnancy rate of IUI (P 0.05). Conclusion: the number of cycles, the percentage of forward motility sperm, the age of TPMSC and the morphology of sperm are the important factors affecting the clinical pregnancy rate of IUI. The thickness and shape of endometrium had no significant effect on the success rate of IUI.
【作者单位】：潍坊市妇幼保健院;潍坊医学院;
【分类号】：R714.8

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