输卵管机械疏通联合臭氧注射在输卵管阻塞性不孕症治疗中的应用观察

发布时间：2018-06-12 14:49

本文选题：不孕症 + 输卵管阻塞　；参考：《山东医药》2017年03期

【摘要】：目的观察输卵管机械疏通(输卵管再通术)联合臭氧注射治疗输卵管阻塞性不孕症的临床疗效。方法输卵管阻塞性不孕症患者105例,随机分为观察组53例、对照组52例。观察组在血管造影引导下行输卵管再通术联合臭氧输卵管内注射治疗;对照组仅行输卵管再通术。分别于术后3 d、1周及1个月门诊通液观察并计算输卵管通畅率;记录术后6~12个月宫内妊娠率;术后3个月行子宫输卵管造影(HSG)检查评价疗效;观察并发症发生情况。结果观察组术后3 d、1周、1个月输卵管通畅率分别为100%、96.23%、94.34%,对照组分别为94.23%、88.46%、84.62%,两组相比,P0.05。术后3个月,观察组手术有效率为90.57%,高于对照组的75.00%(P均0.05)。随访6~12个月,观察组宫内妊娠率为60.38%,高于对照组的40.38%(P0.05)。观察组和对照组分别有38、11例出现术中下腹部胀痛,均可忍受;观察组和对照组分别有17、8例出现轻度恶心、呕吐等血管迷走神经反应,对症处理后均于30 min内缓解;所有患者术后无继发感染,无子宫、输卵管穿孔等严重并发症发生。结论输卵管机械疏通联合臭氧注射治疗输卵管阻塞性不孕症输卵管复通率高,术后宫内妊娠率高,不良反应较轻。
[Abstract]:Objective to observe the clinical effect of tubal mechanical recanalization combined with ozone injection in the treatment of oviduct obstructive infertility. Methods 105 patients with oviduct obstructive infertility were randomly divided into observation group (53 cases) and control group (52 cases). The observation group received fallopian tube recanalization guided by angiography combined with ozone intrafallopian tube injection, while the control group only underwent fallopian tube recanalization. The rate of tubal patency was observed and calculated at 1 week and 1 month after operation, the intrauterine pregnancy rate was recorded from 6 to 12 months after operation, the curative effect was evaluated by hysterosalpingography at 3 months after operation, and the occurrence of complications was observed. Results the patency rate of oviduct in the observation group was 100, 96.23 and 94.34, respectively, and that in the control group was 94.238.46 and 84.62, respectively, compared with P0.05 in the two groups. 3 months after operation, the effective rate of operation in the observation group was 90.57, which was higher than that in the control group (75.00 and 0.05). The rate of intrauterine pregnancy in the observation group was 60.38, which was higher than that in the control group (40.38). In the observation group and the control group, there were 38 cases of pain in the lower abdomen, which could be tolerated, and 178 cases in the observation group and the control group, such as slight nausea, vomiting and other vasovagal nerve reactions, which were relieved within 30 min after symptomatic treatment. No secondary infection, uterus, tubal perforation and other serious complications occurred in all patients. Conclusion the rate of fallopian tube recanalization and intrauterine pregnancy is high and the adverse reaction is mild in patients with oviduct obstructive infertility treated by oviduct mechanical dredging combined with ozone injection.
【作者单位】：中国人民解放军第97医院;中国人民解放军95829部队门诊部;
【分类号】：R711.6

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