产妇围产期医院感染临床特征与病原菌监测分析

发布时间：2018-06-13 06:13

本文选题：妊娠期 + 孕妇　；参考：《中华医院感染学杂志》2015年14期

【摘要】：目的探讨妊娠期孕妇围产期医院感染临床特征及病原菌耐药性,为控制医院围产期感染提供依据。方法回顾性分析2011年11月-2013年11月医院分娩的1 800例产妇临床资料,统计医院感染发生率、感染部位、病原菌分布及对抗菌药物耐药率;采用SPSS 21.0统计软件进行分析。结果 1 800例产妇发生医院感染32例,感染率1.8%;医院感染主要发生部位为呼吸道8例占25.0%,手术切口6例占18.8%,会阴伤口5例占15.6%,泌尿道5例占15.6%;阴道手术产者医院感染发生率显著高于阴道自然分娩和剖宫产(P0.05);32例医院感染患者分离出71株病原菌,其中革兰阳性菌27株占38.0%、革兰阴性菌41株占57.8%、真菌3株占4.2%;革兰阳性菌对万古霉素、利福平、利奈唑胺耐药率为0。结论妊娠期孕妇产后医院感染病原菌以革兰阴性菌为主,了解产妇医院感染临床特征及病原菌耐药率,并制定预防措施降低产妇医院感染率,从而提高产妇及新生儿预后。
[Abstract]:Objective to investigate the clinical characteristics and pathogens resistance of nosocomial infection in pregnant women during perinatal period so as to provide evidence for the control of nosocomial infection. Methods the clinical data of 1,800 pregnant women who were delivered in hospital from November 2011 to November 2013 were analyzed retrospectively. The incidence of nosocomial infection, the location of infection, the distribution of pathogenic bacteria and the rate of drug resistance to antibiotics were analyzed by SPSS 21.0 software. Results 32 cases of nosocomial infection occurred in 1,800 cases of puerpera. Nosocomial infection occurred in 8 cases of respiratory tract (25.0%), surgical incision of 6 cases (18.8%), perineum wound (5 cases) and urinary tract (5 cases). The incidence of nosocomial infection in vaginal operation delivery was significantly higher than that in vaginal spontaneous delivery and dissection. 71 strains of pathogenic bacteria were isolated from 32 patients with nosocomial infection. Among them, 27 Gram-positive bacteria accounted for 38.0%, 41 Gram-negative bacteria accounted for 57.8%, 3 fungi accounted for 4.2%, and Gram-positive bacteria were resistant to vancomycin, rifampicin and linazolamine. Conclusion Gram-negative bacteria are the main pathogens of postpartum nosocomial infection of pregnant women. To understand the clinical characteristics of nosocomial infection and the rate of drug resistance of pathogens, and to make preventive measures to reduce the nosocomial infection rate of puerpera, so as to improve the prognosis of puerpera and newborns.
【作者单位】：珠海中山大学附属第五医院妇产科;
【基金】：广东省医学科研基金资助项目(A2013855)
【分类号】：R714.7

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