血清蛋白及电解质水平与未足月妊娠特发性羊水过少的相关性研究

发布时间：2018-06-15 23:03

本文选题：羊水过少 + 蛋白质　；参考：《中国全科医学》2015年29期

【摘要】：目的探讨血清蛋白及电解质K+、Na+、Cl-水平与未足月妊娠特发性羊水过少的相关性。方法选取2010—2014年于温州医科大学第一附属医院定期产检的未足月妊娠羊水过少及羊水偏少孕妇73例,另选择同期未足月妊娠羊水正常孕妇51例。由B超室同一名高年资医师测量羊水指数(AFI),取外周静脉血测定总蛋白、清蛋白及电解质K+、Na+、Cl-水平。结果 3组年龄、孕周及初产妇、高龄产妇比例比较,差异均无统计学意义(P0.05)。3组总蛋白、清蛋白、球蛋白水平比较,差异有统计学意义(P0.05);其中,羊水偏少组、羊水过少组总蛋白、球蛋白水平低于羊水正常组,羊水过少组清蛋白水平低于羊水正常组(P0.05)。3组清蛋白/球蛋白比例(A/G)及K+、Na+、Cl-水平比较,差异均无统计学意义(P0.05)。血清总蛋白、清蛋白及球蛋白均分别与AFI呈正相关(r=0.32、0.27、0.23,P0.05),A/G及K+、Na+、Cl-与AFI均无直线相关性(P0.05)。结论特发性羊水过少孕妇血清蛋白水平降低,蛋白可能参与了羊水减少的过程,但未发现血清电解质水平与特发性羊水过少的发生有关。
[Abstract]:Objective to investigate the correlation between serum protein and electrolyte K+, Na+, Cl- level and idiopathic amniotic fluid oligohydramnios in non term pregnancy. Methods 73 pregnant women with oligohydramnios and oligohydramnios from 2010 to 2014 at the First Affiliated Hospital of Wenzhou Medical University were selected, and 51 cases of normal pregnant women with amniotic fluid in the same period were selected. The same high year physician measured the amniotic fluid index (AFI) and measured total protein, albumin and electrolyte K+, Na+, Cl- level in peripheral venous blood. The results showed that there was no significant difference (P0.05) in the total protein, albumin and globulin levels in the 3 groups of age, pregnant and early parturients and in the older women (P0.05). The total protein of amniotic fluid group, oligohydramnios group total protein and globulin level were lower than normal group of amniotic fluid. The level of albumin in oligohydramnios group was lower than that of normal amniotic fluid group (P0.05).3 group (A/G) and K+, Na+, Cl- level, the difference was not statistically significant (P0.05). Serum total protein, albumin and globulin were respectively positive with AFI. The correlation (r=0.32,0.27,0.23, P0.05), A/G and K+, Na+, Cl- and AFI had no linear correlation (P0.05). Conclusion the serum protein level of pregnant women with idiopathic oligohydramnios decreased and the protein may be involved in the process of amniotic fluid reduction, but the serum electrolyte level was not found to be related to the occurrence of idiopathic oligohydramnios.
【作者单位】：温州医科大学附属第一医院产科;
【基金】：浙江省温州市科技局计划项目(Y20120205)
【分类号】：R714.259

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