卵巢交界性肿瘤与早期上皮性卵巢癌的临床特点对比分析

发布时间：2018-06-22 20:32

本文选题：卵巢交界性肿瘤 + 上皮性卵巢癌　；参考：《大连医科大学》2014年硕士论文

【摘要】：目的：比较卵巢交界性肿瘤与早期上皮性卵巢癌的临床特点，鉴别存在于两者间的高危因素，提高术前诊断率。方法：收集大连医科大学附属妇产医院从2008年1月到2012年12月因卵巢肿瘤而收入院的患者的诊疗记录，经术后病理明确诊断为卵巢交界性肿瘤或I期上皮性卵巢癌。其中：卵巢交界性肿瘤患者（BOT组）90例；I期上皮性卵巢癌患者（EOT组）72例。对两组患者的一般情况、临床表现、辅助检查、手术及术后病理情况进行对比分析。结果：BOT组和EOC组发病的平均年龄为（41.10±10.11）岁和（53.61±7.25）岁，P=0.002，存在统计学差异；在未绝经患者中，两组的平均年龄为（38.16±7.56）岁和（45.67±4.61）岁，P=0.001，存在统计学差异；两组间绝经患者所占的比例也存在统计学差异；但在绝经患者中，两组的发病年龄没有统计学差异。两组间肿瘤家族病史所占比例分别为1.11%、8.33%，P=0.025，存在统计学差异，在合并子宫内膜异位症、肿瘤发病位置及盆腔积液等情况中没有统计学差异。两组中肿物实性部分大小的平均值分别为（29.00±14.80）mm vs.（47.20±33.56）mm，P=0.017，，存在统计学差异，但在肿物大小、实性部分比例、RI值等方面无统计学差异。 CEA在两组间升高情况下的平均值分别为52.40ng/ml和7.73ng/ml，P0.001，存在统计学差异。而CA125与CEA的数值在两组间及CA125在两组间升高情况下的平均值均无统计学差异。两组间在术后病理类型的分布上存在统计学差异(P0.001)。结论：通过回顾性研究，比较卵巢交界性肿瘤与I期上皮性卵巢癌的临床特点，就本研究而言，与早期上皮性卵巢癌相比，卵巢交界性肿瘤的患者在发病年龄、绝经情况、肿瘤家族史、超声提示肿物实性部分大小、肿瘤标志物升高情况及病理类型等方面均有所不同。
[Abstract]:Objective: to compare the clinical features of borderline ovarian tumor and early epithelial ovarian cancer, to differentiate the high risk factors between them and to improve the preoperative diagnosis rate. Methods: the records of diagnosis and treatment of patients admitted to Dalian Medical University affiliated Gynecology Hospital from January 2008 to December 2012 due to ovarian tumors were collected and diagnosed as borderline ovarian tumors or stage I epithelial ovarian cancer by postoperative pathology. There were 72 cases of epithelial ovarian cancer (EOT group) in 90 cases of ovarian borderline tumor (bot group). The general condition, clinical manifestation, auxiliary examination, operation and postoperative pathology of the two groups were compared and analyzed. Results the mean age of onset in the two groups was (41.10 卤10.11) years and (53.61 卤7.25) years old (P 0.002), and the mean age of the two groups was (38.16 卤7.56) years old and (45.67 卤4.61) years old (P 0.001). There was also a statistical difference in the proportion of menopausal patients between the two groups, but there was no significant difference in onset age between the two groups. The proportion of family history of tumor was 1.118.33 and 0.025 respectively between the two groups. There was no statistical difference between the two groups in the cases of endometriosis, location of tumor and pelvic effusion. The mean size of solid mass in the two groups was (29.00 卤14.80) mm vs. (卤47.20 卤33.56) mmP0. 017 respectively, there was statistical difference between the two groups, but in the tumor size, There was no significant difference in RI value between the two groups, but the average value of 52.40ng/ml was 7.73 ng / ml / ml P 0.001 in the two groups respectively, and there was statistical difference between the two groups. However, there was no significant difference in the values of CA125 and CEA between the two groups and the mean values of CA125 in both groups. There was statistical difference in the distribution of postoperative pathological types between the two groups (P 0.001). Conclusion: the clinical characteristics of ovarian borderline tumor and stage I epithelial ovarian cancer were compared by retrospective study. In this study, the age of onset and menopause of borderline ovarian cancer were compared with those of early epithelial ovarian cancer. The family history of tumor, the size of solid tumor, the elevation of tumor markers and pathological types were different.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.31

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