辅助生殖促排卵药物治疗专家共识

发布时间：2018-06-23 04:10

本文选题：辅助生殖技术(ART) + 促排卵　；参考：《生殖与避孕》2015年04期

【摘要】：辅助生殖技术(ART)的重要内容之一是促排卵治疗,其应用改善了临床妊娠率,但多胎妊娠、卵巢过度刺激综合征(OHSS)等并发症发生几率较高。促排卵最常用药物为克罗米芬(CC),芳香化酶抑制剂、促性腺激素(Gn)类和促性腺激素释放激素类似物(Gn RHa),包括激动剂(Gn RH-a)和拮抗剂(Gn RH-A)近年来的应用也逐渐增加。各种药物有不同的适应证、禁忌证和用药方案,另外还可使用其他促排卵辅助药物,如口服避孕药(OC)、二甲双胍、多巴胺受体激动剂等,这些促排卵治疗效果可通过常用的疗效评估指标及计算方法来统计。中华医学会生殖医学分会部分专家结合近年来国内、外相关领域研究进展及临床应用,对促排卵药物在ART中的应用达成共识,以指导规范的临床应用。
[Abstract]:One of the important contents of art is ovulation therapy, which can improve the clinical pregnancy rate, but the incidence of complications such as multiple pregnancy and ovarian hyperstimulation syndrome (OHSS) is higher. The use of clomiphene (CC), aromatase inhibitor, gonadotropin (Gn) and gonadotropin releasing hormone analogue (GnRHa), including agonists (Gn RH-a) and antagonists (Gn RH-A), has been increasing in recent years. Various drugs have different indications, contraindications and protocols, as well as other ovulatory adjuvants, such as oral contraceptives (OC), metformin, dopamine receptor agonists, etc. These ovulatory therapeutic effects can be counted by commonly used evaluation indexes and calculation methods. Some experts from the Reproductive Medicine Branch of the Chinese Medical Association have reached a consensus on the application of ovulation promoting drugs in art in order to guide the standard clinical application in combination with the research progress and clinical application in the domestic and foreign related fields in recent years.
【作者单位】：中华医学会生殖医学分会;北京大学第三医院;南京医科大学第一附属医院;江苏省妇幼保健院;四川大学华西第二医院;华西妇产儿童医院;广西省妇幼保健院;新疆医科大学第一附属医院;第四军医大学唐都医院;浙江大学医学院附属妇产科医院;山东大学附属生殖医院;贵阳医学院附属医院;中山大学附属第一医院;邵逸夫医院;上海交通大学附属仁济医院;华中科技大学同济医学院附属同济医院;郑州大学第一附属医院;中南大学生殖与干细胞工程研究所;山西省妇幼保健院生殖医学中心;
【分类号】：R714.8

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