子宫肌瘤对双胎胎儿生长发育及新生儿结局的影响

发布时间：2018-06-23 18:57

本文选题：子宫肌瘤 + 双胎　；参考：《首都医科大学学报》2015年04期

【摘要】：目的前瞻性评估子宫肌瘤对双胎胎儿生长发育及新生儿结局的影响。方法选取在首都医科大学附属北京妇产医院建档并于2013年6月至2014年12月分娩的双胎妊娠合并子宫肌瘤患者共46例作为研究组,以及双胎妊娠无肌瘤者63例作为对照组,观察并记录其孕早期、中期、晚期B超监测胎儿生长发育指标、新生儿出生情况及妊娠结局。结果与对照组相比,双胎妊娠合并子宫肌瘤患者的年龄〔(35.04±4.24)岁vs(31.67±3.56)岁,P=0.000〕和孕前体质量指数〔(21.46±3.69)kg/m2vs(20.77±2.38)kg/m2,P=0.009〕明显增加,且在11~14周B超的羊水最大暗区垂直深度明显降低〔(3.14±0.55)cm vs(3.38±0.55)cm,P=0.001)〕,差异具有统计学意义。然而,其他孕早、中、晚期的生长发育指标、新生儿出生情况及妊娠结局差异均无统计学意义。结论子宫肌瘤对双胎胎儿生长发育及新生儿结局的影响并不明显。但考虑到双胎妊娠本身是妊娠的一项高危因素,对双胎妊娠合并子宫肌瘤患者,更应加强对其进行密切的监护和管理,从而使母、儿得到更合理、更安全的治疗。
[Abstract]:Objective to prospectively evaluate the effect of uterine leiomyoma on the growth and development of twin fetus and neonatal outcome. Methods A total of 46 cases of twin pregnancy complicated with uterine leiomyoma were selected from Beijing Maternity Hospital affiliated to Capital Medical University from June 2013 to December 2014 as study group and 63 cases of twin pregnancy without leiomyoma as control group. To observe and record the early, middle and late stage of pregnancy, to monitor fetal growth and development, newborn birth and pregnancy outcome. Results compared with the control group, the age (35.04 卤4.24) years and the pregestational mass index (21.46 卤3.69) kg/m2vs (20.77 卤2.38) kg / m ~ (2) P ~ (2 +) P ~ (0. 009) of twin pregnancy with uterine leiomyoma were significantly increased, and the vertical depth of the maximum dark area of amniotic fluid was significantly decreased (3.14 卤0.55) cm vs (3.38 卤0.55) cm ~ (-1),) at 1114 weeks. The difference is statistically significant. However, there were no significant differences in growth and development indexes, birth status and pregnancy outcome of other early, middle and late pregnancy. Conclusion the effect of uterine leiomyoma on the growth and development of twin fetus and neonatal outcome is not obvious. But considering that twin pregnancy itself is a high risk factor of pregnancy, it is necessary to strengthen the close monitoring and management of twin pregnancy complicated with uterine leiomyoma, so that the mother and the baby can get more reasonable and safe treatment.
【作者单位】：首都医科大学附属北京妇产医院妇科;
【基金】：北京市科技计划项目(Z131107002213090) 北京市医院管理局临床医学发展专项(ZYLX201510)~~
【分类号】：R737.33;R714

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