男性因素对体外受精-胚胎移植妊娠结局的影响

发布时间：2018-06-25 10:00

本文选题：男性因素 + 妊娠结局　；参考：《中华生殖与避孕杂志》2017年06期

【摘要】：目的探讨男性因素对体外受精-胚胎移植(IVF-ET)妊娠结局的影响。方法回顾性分析首次行IVF-ET的新鲜移植周期,共2 806例,对不同妊娠结局组的男性因素进行比较,并运用Logistic回归方程分析各种男性因素对IVF-ET妊娠结局的影响。结果妊娠组的男性年龄[(32.5±4.3)岁]小于未妊娠组[(32.9±4.4)岁],活产组的男性年龄[(32.4±4.3)岁]和卵泡刺激素(FSH)[(5.3±2.5)IU/L]均小于未活产组[(33.0±4.4)岁,(5.5±2.6)IU/L],流产组的男性年龄[(33.5±4.3)岁]、FSH[(5.9±3.0)IU/L]和体质量指数(BMI)[(24.1±3.5)kg/m2]均大于未流产组[(32.4±4.3)岁,(5.3±2.5)IU/L,(23.5±3.3)kg/m2],差异有统计学意义(P0.05);经多因素回归分析,通过控制女方因素的影响后,未见所研究男性因素对IVF的妊娠结局有影响(P0.05)。结论男性因素协同女性因素共同影响IVF-ET的妊娠结局,男性高龄、高FSH、高BMI者的妊娠和活产机会可能较低,流产率可能较高。
[Abstract]:Objective to investigate the effect of male factors on in vitro fertilization-embryo transfer (IVF-et) pregnancy outcome. Methods A total of 2 806 cases of fresh transplantation of IVF-ET were retrospectively analyzed. The male factors of different pregnancy outcome groups were compared, and the influence of various male factors on IVF-ET pregnancy outcome was analyzed by Logistic regression equation. Results the male age in pregnancy group [(32.5 卤4.3) years] was lower than that in non-pregnancy group [(32.9 卤4.4) years], the male age in live birth group [(32.4 卤4.3) years] and follicle stimulating hormone (FSH) [(5.3 卤2.5) IUP] were lower than those in non-live birth group [(33.0 卤4.4) years, (5.5 卤2.6) IUU / L], the male age in abortion group was [(33.5 卤4.3) years old] FSH [(5.9 卤3.0) IUL] and body mass index [(24.1 卤3.5) kg/m2]. In the group without abortion [(32.4 卤4.3) years old, (5.3 卤2.5) IU / L, (23.5 卤3.3) kg/m2], the difference was statistically significant (P0.05). After controlling the influence of female factors, there was no effect of male factors on the pregnancy outcome of IVF (P0.05). Conclusion the pregnancy outcome of IVF-ET is influenced by male factors and female factors. The pregnancy and live birth chances may be lower and the abortion rate may be higher in the elderly, high FSHs and high BMI men.
【作者单位】：中山大学孙逸仙纪念医院妇产科生殖中心;广东省佛山市禅城区中心医院妇产科;
【分类号】：R714.8

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