子宫颈腺样基底细胞癌12例临床病理特征分析

发布时间：2018-06-25 21:34

本文选题：子宫颈肿瘤 + 腺样基底细胞癌　；参考：《临床与实验病理学杂志》2015年05期

【摘要】：目的探讨子宫颈腺样基底细胞癌的临床病理学特征。方法回顾性分析12例子宫颈腺样基底细胞癌患者的临床病理资料、组织学特征及免疫表型,并复习相关文献。结果 12例子宫颈腺样基底细胞癌患者年龄36~70岁,平均53.3岁。5例(41.7%)有阴道出血症状,12例中8例行全子宫切除术,其余4例行子宫颈锥切术。镜下见12例均伴子宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN),癌细胞呈巢状、条索状向子宫颈间质浸润性生长,癌细胞体积小,形态较一致,细胞排列紧密,胞质稀少,胞核深染。12例癌巢中央均可见腺腔样分化,其中2例同时伴部分鳞状细胞分化及轻微间质水肿,癌巢周边细胞呈栅栏状排列。肿瘤浸润深度0.5~10 mm,平均4.12 mm。2例可见脉管癌栓。10例患者随访3~78个月,均无复发和转移,2例失访。结论子宫颈腺样基底细胞癌好发于绝经后妇女,常伴CIN,预后良好,因其具有腺样结构及浸润性生长方式,在诊断时需与腺样囊性癌等肿瘤鉴别。
[Abstract]:Objective to investigate the clinicopathological features of adenoid basal cell carcinoma of the cervix. Methods the clinicopathological features and immunophenotypes of 12 patients with adenoid basal cell carcinoma of the cervix were analyzed retrospectively. Results the age of 12 patients with adenoid basal cell carcinoma of the cervix was 3670 years old (mean 53.3 years old, 41.7%). Of the 12 cases with vaginal bleeding symptoms, 8 cases underwent hysterectomy and the other 4 cases underwent cervical conization. Under microscope, 12 cases of cervical intraepithelial neoplasia (cervical intraepithelial neoplasia cin) were found. The cancer cells were nesting and striped to the cervical stroma. The cancer cells were small in size, uniform in shape, compact in arrangement and rare in cytoplasm. In the center of the cancer nest, 2 cases were accompanied with partial squamous cell differentiation and slight interstitial edema, and the cells around the cancer nest were in a palisade shape. The depth of tumor invasion was 0. 5 ~ 10 mm, with an average of 4. 12 mm.2. 10 cases were followed up for 3 ~ 78 months. No recurrence or metastasis occurred in 2 cases. Conclusion Adenoid basal cell carcinoma of the cervix is more common in postmenopausal women, often accompanied by CIN.The prognosis is good. Because of its glandular structure and invasive growth pattern, adenoid cystic cell carcinoma should be distinguished from adenoid cystic carcinoma in diagnosis.
【作者单位】：江西省妇幼保健院病理科;江西护理职业技术学院生理教研室;
【分类号】：R737.33

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